| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.170 | Biomarker | disease | BEFREE | PECAM-1 is a kind of cell adhesion molecule, which plays an important role in coronary artery disease. | 28512385 | 2017 | ||||
|
0.170 | AlteredExpression | disease | BEFREE | Further analysis revealed reduced phospho-SHP2 (associated with CD31 activation) and phospho-signal transducer and activator of transcription-5 (STAT-5) (associated with FoxP3 transcription) levels in CD31<sup>+</sup> Tr cells of CHD patients, suggesting that decreased FoxP3 expression in CD31<sup>+</sup> Tr cells might be because of attenuated SHP2 and STAT-5 activation. | 27997991 | 2017 | ||||
|
0.170 | GeneticVariation | disease | GWASCAT | A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. | 21378988 | 2011 | ||||
|
0.170 | GeneticVariation | disease | GWASDB | A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. | 21378988 | 2011 | ||||
|
0.170 | GeneticVariation | disease | BEFREE | Genetic analyses of platelet-endothelial cell adhesion molecule-1 (PECAM-1), a key adhesion molecule in the progression of atherosclerosis, have provided conflicting results regarding the role of variation within the PECAM-1 gene and risk for coronary heart disease. | 19183069 | 2009 | ||||
|
0.170 | GeneticVariation | disease | BEFREE | Studies have investigated an association between coronary heart disease (CHD) and single nucleotide polymorphisms (SNP) located in functionally important domains of the PECAM-1/CD31 gene, with contrasting results. | 17460171 | 2007 | ||||
|
0.170 | GeneticVariation | disease | BEFREE | Association of Leu125Val polymorphism of platelet endothelial cell adhesion molecule-1 (PECAM-1) gene & soluble level of PECAM-1 with coronary artery disease in Asian Indians. | 15756041 | 2005 | ||||
|
0.170 | GeneticVariation | disease | BEFREE | A few studies have investigated an association between coronary heart disease and single nucleotide polymorphisms (SNPs) located in functionally important domains of the PECAM-1/CD31 gene. | 15265022 | 2004 | ||||
|
0.170 | AlteredExpression | disease | BEFREE | These data demonstrate that the PECAM-1 gene is responsive to shear stress in vitro and that decreased PECAM-1 gene expression in 53A carriers may influence reduced progression of vessel stenosis in patients with coronary artery disease. | 12732396 | 2003 |