×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
Biomarker
disease
GENOMICS_ENGLAND
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
BEFREE
Crohn's disease is a chronic inflammatory bowel disorder that has been associated with polymorphisms in the genes encoding the pattern-recognition receptor NOD2 and the autophagic regulator ATG16L1 .
20144769
2010
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
Biomarker
disease
BEFREE
ATG16L1 and NOD2 were found to contribute independently to CD risk.
18671817
2008
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
Biomarker
disease
BEFREE
ATG16L1 and NOD2 are components of an autophagy-mediated antibacterial pathway that is altered in a cell- and function-specific manner by CD -associated mutations.
20637199
2010
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
Biomarker
disease
BEFREE
ATG16L1 and TNFSF15 are associated with CD in Taiwan.
21930071
2011
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
BEFREE
Autophagy-related 16 like-1 (ATG16L-1 ), immunity-related GTPase-M (IRGM), and nucleotide-binding oligomerization domain-containing 2 (NOD2) regulate autophagy, and variants in these genes have been associated with predisposition to Crohn's disease (CD).
22285936
2012
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
Biomarker
disease
BEFREE
ATG16L1 , an essential component for autophagy and a risk gene for Crohn's disease , contains two binding sites in the 3'UTR for miR-17 family, including miRs-20a, -93, -106a, and -106b.
23899543
2013
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
BEFREE
ATG16L1 and IL23R variants and genetic susceptibility to crohn's disease : mode of inheritance based on meta-analysis of genetic association studies.
25738374
2015
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
Biomarker
disease
BEFREE
ATG16L1 , a protein essential for early stages of autophagy, has been implicated in the pathogenesis of Crohn's disease .
25767270
2015
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
AlteredExpression
disease
BEFREE
ATG16L1 and LC3 expression was analyzed in the inflamed ileum and colon of 28 patients with Crohn's disease (CD ), 14 with ulcerative colitis (UC) and 23 controls by western blot.
27335178
2016
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
BEFREE
ATG16L1 polymorphisms have been linked to the development of Crohn's disease (CD ), and phosphorylation of CD -associated ATG16L1 T300A (caATG16L1) has been hypothesized to contribute to cleavage and autophagy dysfunction.
31267703
2019
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
BEFREE
Thr300Ala polymorphism in ATG16L1 was reported as a susceptibility factor to Crohn's disease (CD ).
19575361
2009
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
BEFREE
A genetic risk factor associated specifically with Crohn's disease is a variant in ATG16L1 that reduces autophagy.
27435106
2017
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
BEFREE
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 .
17200669
2007
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
LHGDN
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 .
17200669
2007
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
BEFREE
A genome-wide association study has shown an association of Crohn's disease with the autophagy related 16-like 1 gene.
19026604
2009
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
GWASCAT
A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.
22936669
2013
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
GWASDB
A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.
22936669
2013
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
GWASCAT
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
22412388
2012
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
GWASDB
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
22412388
2012
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
BEFREE
A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5.
17484864
2007
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
Biomarker
disease
LHGDN
A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5.
17484864
2007
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
BEFREE
All nine ATG16L1 gene variants analyzed displayed highly significant associations with CD demonstrating a CD -protective effect for the minor allele.
18162085
2008
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
BEFREE
An alteration in ATG16L1 stability in Crohn disease .
25136803
2014
×
Entrez Id:
55054
Gene Symbol:
ATG16L1
ATG16L1
0.700
GeneticVariation
disease
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016