Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
0.700 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
0.700 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.700 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
0.700 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
0.700 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
0.620 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 3593
Gene Symbol: IL12B
IL12B
0.600 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.500 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
0.500 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.500 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
0.500 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 6584
Gene Symbol: SLC22A5
SLC22A5
0.400 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.330 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 9051
Gene Symbol: PSTPIP1
PSTPIP1
0.110 Biomarker disease HPO
Entrez Id: 3507
Gene Symbol: IGHM
IGHM
0.100 Biomarker disease HPO
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
0.700 GeneticVariation disease BEFREE <b>Background:</b> The interleukin 23 receptor gene (<i>IL23R</i>) is strongly associated with Crohn's disease (CD). 31799225 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 Biomarker disease BEFREE <b>Conclusion:</b> In suspected CD, low serum iron and elevated CRP had a statistically significant association with CD diagnosis, being helpful to identify patients with higher CD probability before SBCE. 31378118 2019
Entrez Id: 196
Gene Symbol: AHR
AHR
0.140 GeneticVariation disease BEFREE <b>Conclusions</b><i>AhR</i> (rs2158041) might be a susceptible locus for CD, especially for the two subtypes: ileal CD and stricture CD. 31405308 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 AlteredExpression disease BEFREE <b>Conclusions:</b> Baseline CRP level and CRP reduction rate might be clinical predictors for PNR or LOR to anti-TNF in patients with CD, and could guide proper therapeutic interventions in patients with CD. 31303093 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE <b>Methods:</b> Free thiols were quantified in plasma of patients with CD in clinical remission [according to the Harvey Bradshaw Index (HBI)] and healthy controls and adjusted for plasma albumin. 31080419 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.370 AlteredExpression disease BEFREE <b>Methods:</b> We measured serum levels of growth hormone binding protein (GHBP) and insulin-like growth factor-I (IGF-I), and growth hormone receptor (GHR) gene expression in peripheral blood mononuclear cells of 21 patients with CD (before and after therapy) and in 27 age-sex-matched controls. 30483486 2018
Entrez Id: 2690
Gene Symbol: GHR
GHR
0.020 AlteredExpression disease BEFREE <b>Results:</b> At diagnosis, significantly lower insulin-like growth factor-I and growth hormone binding protein levels were found in the CD group compared to the controls. 30483486 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 Biomarker disease BEFREE <b>Results:</b> Following infliximab, FC and CRP declined (<i>p</i> < .0001) along with HBi for CD and pMCS for UC. 31499013 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.500 Biomarker disease BEFREE <i>STAT3</i> Genotypic Variant <i>rs744166</i> and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn's Disease. 31321245 2019
Entrez Id: 51561
Gene Symbol: IL23A
IL23A
0.100 Biomarker disease BEFREE <i>STAT3</i> Genotypic Variant <i>rs744166</i> and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn's Disease. 31321245 2019