| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.430 | Biomarker | disease | BEFREE | Therefore, herbs-partitioned moxibustion combined with acupuncture can prevent intestinal epithelial mesenchymal transition by inhibiting abnormal expression of TGF<i>β</i>1, T<i>β</i>R2, Smad3, and Snail in the TGF-<i>β</i>1-Smad-Snail pathway in Crohn's disease. | 31275422 | 2019 | ||||
|
0.430 | AlteredExpression | disease | BEFREE | The high SMAD7 immunoreactivity and lack of p-SMAD3 expression in the LP suggests defective TGF-β signaling in the LP in EE similar to a previously reported SMAD7-mediated inflammatory pathway in refractory CD and Crohn's disease. | 29415065 | 2018 | ||||
|
0.430 | GeneticVariation | disease | GWASCAT | Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. | 28067908 | 2017 | ||||
|
0.430 | GeneticVariation | disease | GWASCAT | Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. | 26974007 | 2016 | ||||
|
0.430 | GeneticVariation | disease | GWASCAT | Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. | 26301688 | 2015 | ||||
|
0.430 | GeneticVariation | disease | GWASCAT | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. | 26192919 | 2015 | ||||
|
0.430 | GeneticVariation | disease | BEFREE | SMAD3 gene variant is a risk factor for recurrent surgery in patients with Crohn's disease. | 24461721 | 2014 | ||||
|
0.430 | GeneticVariation | disease | GWASDB | Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. | 21102463 | 2010 | ||||
|
0.430 | GeneticVariation | disease | GWASCAT | Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. | 21102463 | 2010 | ||||
|
0.430 | Biomarker | disease | CTD_human | Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. | 21102463 | 2010 |