Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4689
Gene Symbol: NCF4
NCF4
0.450 GeneticVariation disease GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
Entrez Id: 4689
Gene Symbol: NCF4
NCF4
0.450 Biomarker disease BEFREE This study found a novel genetic association of RAC2 with Crohn's disease (CD) and replicated the previously reported association of NCF4 with ileal CD. 21900546 2012
Entrez Id: 4689
Gene Symbol: NCF4
NCF4
0.450 Biomarker disease BEFREE Similarly, a pooled analysis using data from two recent studies did not demonstrate associations between the NCF4 (OR = 1.10, 95% CI = 0.91-1.32, P = 0.32) and FAM92B (OR = 1.05, 95% CI = 0.95-1.17, P = 0.36) GWAS lead SNPs and ileal CD. 21472827 2012
Entrez Id: 4689
Gene Symbol: NCF4
NCF4
0.450 GeneticVariation disease BEFREE To investigate whether variants in the NCF4 and ATG4A genes are associated with granuloma formation in a cohort of Israeli patients with CD, exploring demographic and clinical characteristics that differ between granuloma positive and granuloma negative patients. 21122541 2010
Entrez Id: 4689
Gene Symbol: NCF4
NCF4
0.450 GeneticVariation disease BEFREE In contrast to the North American population, PHOX2B, NCF4, FAM92B, and rs224136 are not associated with CD in the European population, whereas NOD2/CARD15, IL23R, and ATG16L1 are strongly associated with CD in both the North American and European populations, confirming these three genes as major CD susceptibility genes in Caucasian populations. 19262523 2009
Entrez Id: 4689
Gene Symbol: NCF4
NCF4
0.450 Biomarker disease LHGDN Our study has demonstrated that IRGM and NCF4 are ileal-specific CD susceptibility factors in New Zealand Caucasians. 18580884 2008
Entrez Id: 4689
Gene Symbol: NCF4
NCF4
0.450 Biomarker disease BEFREE Our study has demonstrated that IRGM and NCF4 are ileal-specific CD susceptibility factors in New Zealand Caucasians. 18580884 2008
Entrez Id: 4689
Gene Symbol: NCF4
NCF4
0.450 Biomarker disease CTD_human Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. 17435756 2007