Gene: ESR1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.270 GeneticVariation disease BEFREE The results of this meta-analysis suggest that A allele of SNP12 in estrogen receptor 1 may increase the risk of cryptorchidism in Asians. 27376826 2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.270 AlteredExpression disease BEFREE MYH7 and ESR1 mRNA levels were higher and lower, respectively, in boys with nonsyndromic cryptorchidism who were fed soy formula. 22906643 2012
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.270 Biomarker disease RGD Altered expression and localization of estrogen receptors alpha and beta in the testes of a cryptorchid rat model. 20951417 2011
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.270 GeneticVariation disease BEFREE ESR1 promoter polymorphism is not associated with nonsyndromic cryptorchidism. 20887985 2011
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.270 Biomarker disease BEFREE SNP12 in ESR1 is not associated with the occurrence of cryptorchidism but is associated with the severity of cryptorchidism. 18452179 2008
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.270 Biomarker disease BEFREE However, in contrast with the Japanese population we found a protective effect for ESR1 SNP12 on cryptorchidism in the Italian population. 17099213 2007
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.270 Biomarker disease BEFREE We have recently suggested that homozygosity for a specific 'AGATA' haplotype within a approximately 50 kb linkage disequilibrium (LD) block of the gene for estrogen receptor alpha (ESR1) may raise the susceptibility to cryptorchidism by enhancing estrogenic effects of environmental endocrine disruptors (EEDs). 17283037 2007
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.270 GeneticVariation disease BEFREE Identification of a specific ESR1 haplotype associated with CO was the main outcome measure. 15899960 2005