Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7450
Gene Symbol: VWF
VWF
0.060 AlteredExpression disease BEFREE Severe hypercortisolism and VWF levels with increased haemostatic activity are strongly associated with VTE in CS. 22585010 2013
Entrez Id: 7450
Gene Symbol: VWF
VWF
0.060 GeneticVariation disease BEFREE This study was undertaken to correlate plasma vWF levels with plasma cortisol and single nucleotide polymorphisms (SNPs) at positions -2659 and -2525 in Cushing syndrome patients in India. 22688555 2012
Entrez Id: 7450
Gene Symbol: VWF
VWF
0.060 GeneticVariation disease BEFREE This is not a constant feature of CS, however; it depends on particular single nucleotide polymorphism (SNP) haplotypes in the VWF gene promoter: haplotype 1 (-3268G/-2709C/-2661A/-2527G) confers a greater risk of VWF upregulation by cortisol than haplotype 2 (-3268C/ -2709T/-2661G/-2527A). 21304226 2011
Entrez Id: 7450
Gene Symbol: VWF
VWF
0.060 Biomarker disease BEFREE Microsatellite (GT)(n) is part of the von Willebrand factor (VWF) promoter region that influences the glucocorticoid-induced increase in VWF in Cushing's syndrome. 20156642 2010
Entrez Id: 7450
Gene Symbol: VWF
VWF
0.060 Biomarker disease BEFREE Our data indicate that two different mechanisms upregulate VWF under hypercortisolism and pregnancy, the latter being independent of the VWF promoter haplotypes sensitive to cortisol excess. 20614575 2010
Entrez Id: 7450
Gene Symbol: VWF
VWF
0.060 Biomarker disease BEFREE Polymorphisms in von Willebrand factor gene promoter influence the glucocorticoid-induced increase in von Willebrand factor: the lesson learned from Cushing syndrome. 18173757 2008