Gene: HFE ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3077
Gene Symbol: HFE
HFE 		0.160 GeneticVariation disease BEFREE We explored the association between mutations in the hemochromatosis (HFE) gene and disease severity in adults with CF. 30291871 2019
Entrez Id: 3077
Gene Symbol: HFE
HFE 		0.160 GeneticVariation disease BEFREE HFE gene mutations modify disease severity in CF, through probable effects on iron homeostasis. 20199637 2010
Entrez Id: 3077
Gene Symbol: HFE
HFE 		0.160 GeneticVariation disease BEFREE The possible implication of the hemochromatosis gene as a CF modifier locus was analyzed because the 2 children had the same genotype. 18078365 2008
Entrez Id: 3077
Gene Symbol: HFE
HFE 		0.160 Biomarker disease BEFREE We determined the genotype of four proposed genetic risk factors for hepatocellular carcinoma [hereditary hemochromatosis (HFE 63 and 282), alpha(1)-antitrypsin deficiency (AAT 342) and cystic fibrosis (CFTR 508)] on formalin-fixed tissue samples, stored for up to 25 years, from 318 patients diagnosed with hepatocellular carcinoma and on plasma or serum samples from 31 of these patients. 15668502 2005
Entrez Id: 3077
Gene Symbol: HFE
HFE 		0.160 GeneticVariation disease LHGDN HFE status of CF allele carriers and CF patients (Delta F508) homozygotes with and without meconium ileus was determined. 12885340 2003
Entrez Id: 3077
Gene Symbol: HFE
HFE 		0.160 Biomarker disease BEFREE HFE status of CF allele carriers and CF patients (Delta F508) homozygotes with and without meconium ileus was determined. 12885340 2003
Entrez Id: 3077
Gene Symbol: HFE
HFE 		0.160 Biomarker disease BEFREE These data are suggestive of a relationship between the development of meconium ileus or other gastrointestinal diseases in CF and the HFE gene. 10464603 1998
Entrez Id: 3077
Gene Symbol: HFE
HFE 		0.160 SusceptibilityMutation disease CLINVAR