Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 213
Gene Symbol: ALB
ALB
0.060 Biomarker disease BEFREE Pressure ulcer risk factors were peripheral vascular disease, end-stage disease, past pressure ulcer history, high risk group for pressure ulcer development, fever, haemoglobin, and albumin (all P < 0.05); only albumin (odds ratio: 0.210, P < 0.001) was significantly associated with pressure ulcer development as an independent risk factor. 30793859 2019
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
0.030 Biomarker disease BEFREE Decubitus CT Myelography for Detecting Subtle CSF Leaks in Spontaneous Intracranial Hypotension. 30819772 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.030 Biomarker disease BEFREE Decubitus CT Myelography for Detecting Subtle CSF Leaks in Spontaneous Intracranial Hypotension. 30819772 2019
Entrez Id: 56302
Gene Symbol: TRPV5
TRPV5
0.010 Biomarker disease BEFREE Pressure ulcer Cat. II-IV incidence on the CuroCell S.A.M. PRO powered reactive air support surface in a high-risk population: A multicentre cohort study in 12 Belgian nursing homes. 31713351 2020
Entrez Id: 9815
Gene Symbol: GIT2
GIT2
0.010 Biomarker disease BEFREE Pressure ulcer Cat. II-IV incidence on the CuroCell S.A.M. PRO powered reactive air support surface in a high-risk population: A multicentre cohort study in 12 Belgian nursing homes. 31713351 2020
Entrez Id: 6542
Gene Symbol: SLC7A2
SLC7A2
0.010 Biomarker disease BEFREE Pressure ulcer Cat. II-IV incidence on the CuroCell S.A.M. PRO powered reactive air support surface in a high-risk population: A multicentre cohort study in 12 Belgian nursing homes. 31713351 2020
Entrez Id: 7114
Gene Symbol: TMSB4X
TMSB4X
0.020 Biomarker disease BEFREE Thymosin β4 promotes faster repair in various chronic human wounds, including pressure ulcers, stasis ulcers, and epidermolysis bullosa lesions. 31649007 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
0.010 Biomarker disease BEFREE Interleukin-1α (IL-1α), vascular endothelial growth factor C (VEGF-C) and heat shock protein 90α (HSP90α) were expressed in the pressure ulcer model at a significantly different level compared to the blanchable erythema or intact skin during the time course. 31757582 2020
Entrez Id: 574444
Gene Symbol: MIR491
MIR491
0.010 GeneticVariation disease BEFREE A functional polymorphism at miR‑491‑5p binding site in the 3'UTR of MMP9 gene confers increased risk for pressure ulcers after hip fracture. 29620239 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.020 GeneticVariation disease BEFREE A functional polymorphism at miR‑491‑5p binding site in the 3'UTR of MMP9 gene confers increased risk for pressure ulcers after hip fracture. 29620239 2018
Entrez Id: 8864
Gene Symbol: PER2
PER2
0.010 Biomarker disease BEFREE After EC was implemented (period 2), 65% of patients stood, 54% walked at least once during their ICU stay, and ICU-acquired pressure ulcers and physical restraint use decreased (period 1 vs 2: 39% vs 23% of patients; 30% vs 26% patient days, respectively; p < 0.001 for both). 30985390 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.220 Biomarker disease RGD Analysis of Gene Expression in Experimental Pressure Ulcers in the Rat with Special Reference to Inflammatory Cytokines. 26177082 2015
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.020 AlteredExpression disease BEFREE Besides, vessel formation and wound healing were enhanced in hESC-MSC-Fb-treated skin tissues compared to PBS- or hESC-MSC-treated skin tissues, along with decreased IL-6 expression at 4 days after the formation of pressure ulcer wound in a mouse model. 30693037 2018
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
0.010 Biomarker disease BEFREE Candesartan, an angiotensin II type 1 receptor blocker, is also able to restore PIV and prevent pressure ulcer formation. 31333501 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
0.060 GeneticVariation disease BEFREE Despite orthogeriatric management, pressure ulcers were significantly associated with a low albumin level (RR 0.90, 95% CI 0.84-0.96; p = 0.003) and history of atrial fibrillation (RR 1.91, 95% CI 1.05-3.46; p = 0.033), coronary artery disease (RR 2.16, 95% CI 1.17-3.99; p = 0.014), and diabetes (RR 2.33, 95% CI 1.14-4.75; p = 0.02). 28852954 2017
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
0.030 Biomarker disease BEFREE Digital subtraction myelography was then performed in patients positive for spinal longitudinal extradural CSF collection primarily in the prone position and in patients negative for spinal longitudinal extradural CSF collection in the lateral decubitus positions. 30923083 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.030 Biomarker disease BEFREE Digital subtraction myelography was then performed in patients positive for spinal longitudinal extradural CSF collection primarily in the prone position and in patients negative for spinal longitudinal extradural CSF collection in the lateral decubitus positions. 30923083 2019
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
0.010 Biomarker disease BEFREE During this work, the interactions between <i>S. aureus</i> and <sub>L</sub>-Cys-g-PCL foam were studied under conditions that simulate decubitus ulcers; namely, pH and exudate. 28104899 2017
Entrez Id: 9033
Gene Symbol: PKD2L1
PKD2L1
0.010 Biomarker disease BEFREE During this work, the interactions between <i>S. aureus</i> and <sub>L</sub>-Cys-g-PCL foam were studied under conditions that simulate decubitus ulcers; namely, pH and exudate. 28104899 2017
Entrez Id: 56287
Gene Symbol: GKN1
GKN1
0.010 Biomarker disease BEFREE Examination was performed with patients in left lateral decubitus position using T2-weighted turbo spin echo sequence in the sagittal plane at rest (TE 89ms, TR 3220ms, FOV 300mm, matrix 512×512, ST 4mm) and ultrafast-T2-weighted-sequence in the sagittal plane with repeating measurements (TE 1.54ms, TR 3.51ms, FOV 400mm, matrix 256×256, ST 6mm). 28629562 2017
Entrez Id: 4327
Gene Symbol: MMP19
MMP19
0.010 AlteredExpression disease BEFREE Expression of MMP-19 was detected by immunohistochemistry in fibroblasts, capillary endothelial cells, and macrophages in the dermal layer of large granulating wounds, as well as in chronic venous and decubitus ulcers. 14708598 2003
Entrez Id: 284697
Gene Symbol: BTBD8
BTBD8
0.020 Biomarker disease BEFREE Factors associated with reductions in functional status over 6 months were (a) institutionalized prior to hospitalization, (b) pressure sore before admission, (c) existing delirium, (d) impaired mobility at baseline, (e) increased APACHE II score upon ICU admission, and (f) use of mechanical ventilation during the ICU stay. 30022689 2020
Entrez Id: 4810
Gene Symbol: NHS
NHS
0.020 GeneticVariation disease BEFREE For this clinical evaluation 230 patients were purposefully sampled across four broad levels of pressure ulcer risk with representation from four secondary care and four community NHS Trusts in England. 28833356 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.030 GeneticVariation disease BEFREE Fourteen postoperative complications in 10 patients (34%) included respiratory failure (14%), pneumonia (7%), urinary infection (10%), bed sores (10%), and CSF leak (7%). 28826916 2018
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
0.030 GeneticVariation disease BEFREE Fourteen postoperative complications in 10 patients (34%) included respiratory failure (14%), pneumonia (7%), urinary infection (10%), bed sores (10%), and CSF leak (7%). 28826916 2018