Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9622
Gene Symbol: KLK4
KLK4
0.140 GeneticVariation disease BEFREE SNPs in three genes (DSPP, KLK4 and AQP5) showed consistent associations with protection against caries. 22508493 2012
Entrez Id: 9622
Gene Symbol: KLK4
KLK4
0.140 GeneticVariation disease BEFREE The aim of the study was to analyze the genotype and allele frequencies of single nucleotide polymorphisms (SNPs) in AMELX, AMBN, TUFT1, TFIP11, MMP20 and KLK4 genes and to prove their association with dental caries occurrence in a population of Polish children. 29068589 2017
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.140 GeneticVariation disease BEFREE Our results showed that VDR BsmI polymorphism was associated with the risk of deciduous tooth decay in Chinese children aged 4-7 years. 28697775 2017
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.140 GeneticVariation disease BEFREE Among the four examined <i>VDR</i> gene polymorphisms, the increased frequency of the CT and CC genotype of the <i>Fok</i> I <i>VDR</i> gene polymorphism was associated with dental caries in 12-year-old adolescent, compared with the controls (<i>X</i><sup>2</sup> = 17.813, <i>p</i> ≤ 0.001). 29259981 2017
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.140 GeneticVariation disease BEFREE Vitamin D Receptor TaqI Gene Polymorphism and Dental Caries in Czech Children. 27889775 2017
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.140 GeneticVariation disease BEFREE The aim of this study was to investigate the relationship between a single nucleotide polymorphism in the vitamin D receptor TaqI locus and dental caries susceptibility in a Chinese population. 26436404 2015
Entrez Id: 9622
Gene Symbol: KLK4
KLK4
0.140 GeneticVariation disease BEFREE Genetic variations in the KLK4 gene may contribute to dental decay. 28445870 2017
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
0.130 GeneticVariation disease BEFREE The purpose of this study was to determine if polymorphisms in MMP2 (rs243865), MMP9 (rs17576), MMP13 (rs2252070), and TIMP2 (rs7501477) were associated with caries. 22710194 2012
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
0.130 GeneticVariation disease BEFREE In conclusion, the genetic polymorphism rs478927 in MMP13 was associated with caries experience and DDE. 30759432 2019
Entrez Id: 744
Gene Symbol: MPPED2
MPPED2
0.120 GeneticVariation disease GWASDB Genome-wide association scan for childhood caries implicates novel genes. 21940522 2011
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
0.110 GeneticVariation disease BEFREE Before and after every removal, images of a color-matching sticker and carious surfaces stained with a caries detector dye were acquired simultaneously using a CCD camera and dentinal tissue samples were removed with a round bur. 15765962 2005
Entrez Id: 119180
Gene Symbol: LYZL2
LYZL2
0.110 GeneticVariation disease GWASDB GWAS of dental caries patterns in the permanent dentition. 23064961 2013
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
0.110 GeneticVariation disease BEFREE A recent genome-wide association study (GWAS) for dental caries nominated the chromosomal region 4q21 near ABCG2, PKD2 and the SIBLING (small integrin-binding ligand N-linked glycoprotein) gene family. 28100911 2017
Entrez Id: 3853
Gene Symbol: KRT6A
KRT6A
0.110 GeneticVariation disease BEFREE Using genetic and intraoral examination data from 573 adults and 449 children, we identified several missense polymorphisms in KRT6A, KRT6B and KRT6C that lead to a higher risk for dental caries. 29357356 2018
Entrez Id: 3854
Gene Symbol: KRT6B
KRT6B
0.110 GeneticVariation disease BEFREE Using genetic and intraoral examination data from 573 adults and 449 children, we identified several missense polymorphisms in KRT6A, KRT6B and KRT6C that lead to a higher risk for dental caries. 29357356 2018
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
0.110 GeneticVariation disease GWASDB GWAS of dental caries patterns in the permanent dentition. 23064961 2013
Entrez Id: 119180
Gene Symbol: LYZL2
LYZL2
0.110 GeneticVariation disease GWASCAT GWAS of dental caries patterns in the permanent dentition. 23064961 2013
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
0.110 GeneticVariation disease GWASCAT GWAS of dental caries patterns in the permanent dentition. 23064961 2013
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
0.100 GeneticVariation disease GWASCAT Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. 31235808 2019
Entrez Id: 8398
Gene Symbol: PLA2G6
PLA2G6
0.100 GeneticVariation disease CLINVAR
Entrez Id: 109
Gene Symbol: ADCY3
ADCY3
0.100 GeneticVariation disease GWASCAT Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. 31235808 2019
Entrez Id: 4739
Gene Symbol: NEDD9
NEDD9
0.100 GeneticVariation disease GWASCAT Consortium-based genome-wide meta-analysis for childhood dental caries traits. 29931343 2018
Entrez Id: 4756
Gene Symbol: NEO1
NEO1
0.100 GeneticVariation disease GWASCAT Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. 31235808 2019
Entrez Id: 6196
Gene Symbol: RPS6KA2
RPS6KA2
0.100 GeneticVariation disease GWASCAT Genome-wide association scan of dental caries in the permanent dentition. 23259602 2012
Entrez Id: 1736
Gene Symbol: DKC1
DKC1
0.100 GeneticVariation disease CLINVAR