Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 29974
Gene Symbol: A1CF
A1CF
0.010 Biomarker disease BEFREE The current study evaluated whether (a) THT+ as indexed by reported dispositional fearfulness mediates the relationship between fear disorders (when unaccompanied by depression) and ASP, and (b) depression moderates relations of THT+ and fear disorders with ASP. 25448265 2015
Entrez Id: 2
Gene Symbol: A2M
A2M
0.300 Biomarker disease PSYGENET Protein abnormalities in adult respiratory distress syndrome, tuberculosis, and cystic fibrosis sera. 2432615 1987
Entrez Id: 2
Gene Symbol: A2M
A2M
0.300 Biomarker disease PSYGENET In the present study we tested two polymorphisms in the alpha-2 macroglobulin gene, a 5 bp deletion at the 5' splice site of exon 18 and a G/A point mutation (V1000I) in exon 24, in a sample of 118 healthy, non demented controls and 238 consecutively recruited gerontopsychiatric patients, diagnosed as: Alzheimer's disease (N=88), mild cognitive impairment (N=32), subjective cognitive complaints (N=54) and depression/other psychiatric disorders (N=64). 11058789 2000
Entrez Id: 51166
Gene Symbol: AADAT
AADAT
0.010 GeneticVariation disease BEFREE In this work, we assessed the relationship between single-nucleotide polymorphisms (SNPs) of KAT1, KAT2 and IDO1 gene encoding, and the risk of depression development. 29777939 2018
Entrez Id: 15
Gene Symbol: AANAT
AANAT
0.300 Biomarker disease PSYGENET The mutant, AANAT knocked down C57BL/6J mice displayed significantly longer times of immobility ("depression"). 11316327 2001
Entrez Id: 57505
Gene Symbol: AARS2
AARS2
0.100 Biomarker disease HPO
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
0.010 GeneticVariation disease BEFREE Our results provide promising evidence that MB-COMT specific genetic variation may represent an as yet unrecognized genetic factor that influences predisposition to depression amongst females. 23351565 2013
Entrez Id: 154664
Gene Symbol: ABCA13
ABCA13
0.010 GeneticVariation disease BEFREE A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression. 19944402 2009
Entrez Id: 10347
Gene Symbol: ABCA7
ABCA7
0.100 Biomarker disease HPO
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 Biomarker disease PSYGENET The present study suggests that the C3435T polymorphism of the MDR1 gene affects the formation of a depression-prone personality trait in Japanese females. 24577069 2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 GeneticVariation disease BEFREE The present study suggests that the C3435T polymorphism of the MDR1 gene affects the formation of a depression-prone personality trait in Japanese females. 24577069 2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 GeneticVariation disease BEFREE Impact of ABCB1 variants on neutrophil depression: a pharmacogenomic study of paclitaxel in 92 women with ovarian cancer. 21955855 2012
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 GeneticVariation disease BEFREE ABCB1 (MDR1) polymorphisms and antidepressant response in geriatric depression. 20555295 2010
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 Biomarker disease BEFREE 182 subjects diagnosed with depression and treated with these drugs were clinically and therapeutically characterized and submitted to the quantification of drug/metabolite plasma concentrations and genotyping of ABCB1, CYP2C9, CYP2C19, and CYP2D6 genes. 31120287 2020
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 GeneticVariation disease BEFREE Results point to the potential importance of ABCB1 variation for personalized medicine approaches to treating depression. 25487678 2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 Biomarker disease PSYGENET Silencing clusterin gene transcription on effects of multidrug resistance reversing of human hepatoma HepG2/ADM cells. 25600802 2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 GeneticVariation disease BEFREE The Influence of C3435T Polymorphism of the ABCB1 Gene on Genetic Susceptibility to Depression and Treatment Response in Polish Population - Preliminary Report. 26664259 2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 GeneticVariation disease BEFREE Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression. 18215618 2008
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 GeneticVariation disease BEFREE BACKGROUND The role of multidrug resistance 1 gene (MDR1 or ABCB1) polymorphism G2677T was studied in relation to paroxetine therapeutic efficacy and its side effects, as well as its association with selected demographic and clinical characteristics of patients with depressive disorder. 29754150 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 Biomarker disease BEFREE Results suggest that antidepressant treatment of depression can be optimized by the clinical application of ABCB1 genotyping. 23880209 2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 GeneticVariation disease BEFREE In this review, we summarize 32 studies investigating the question of whether ABCB1 polymorphisms predict clinical efficacy and/or tolerability of antidepressants in humans and evaluate the clinical application status of ABCB1 genotyping in depression treatment. 27918249 2016
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 GeneticVariation disease BEFREE MDR1 gene polymorphism in Japanese patients with schizophrenia and mood disorders including depression. 17142980 2006
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 Biomarker disease PSYGENET Our findings suggest that single nucleotide polymorphisms in the ABCB1 gene may be indicators of the severity of depression and of the likely S-CIT treatment remission response in MDD. 20859246 2011
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 Biomarker disease PSYGENET Impact of ABCB1 variants on neutrophil depression: a pharmacogenomic study of paclitaxel in 92 women with ovarian cancer. 21955855 2012
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.400 GeneticVariation disease BEFREE Our findings suggest that single nucleotide polymorphisms in the ABCB1 gene may be indicators of the severity of depression and of the likely S-CIT treatment remission response in MDD. 20859246 2011