Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.350 | AlteredExpression | disease | BEFREE | There was a clear pattern of overall suppression of the mediators, especially those noted for their pro-inflammatory role in AD (monocyte chemoattractant protein [MCP]-1, regulated on activation, normal T cell expressed and secreted, cutaneous T-cell-attracting chemokine, Eotaxin, and macrophage inflammatory protein-1α, etc.). | 29853747 | 2018 | ||||
|
0.350 | Biomarker | disease | LHGDN | To investigate whether single-nucleotide polymorphisms of the eotaxin gene are associated with AD, we investigated the genotype and allelic frequencies of -426C-->T, -384A-->G, and 67G-->A SNPs in 130 Italian families. | 18312459 | 2008 | ||||
|
0.350 | Biomarker | disease | CTD_human | Peroxisome proliferator-activated receptor alpha regulates skin inflammation and humoral response in atopic dermatitis. | 18249437 | 2008 | ||||
|
0.350 | GeneticVariation | disease | BEFREE | To investigate whether single-nucleotide polymorphisms of the eotaxin gene are associated with AD, we investigated the genotype and allelic frequencies of -426C-->T, -384A-->G, and 67G-->A SNPs in 130 Italian families. | 18312459 | 2008 | ||||
|
0.350 | GeneticVariation | disease | BEFREE | Eotaxin gene SNPs in the promoter and exon regions are not associated with susceptibility to AD, but two of them in the promoter region are associated with phenotype of AD. | 12234713 | 2002 | ||||
|
0.350 | AlteredExpression | disease | BEFREE | There is an increased expression of eotaxin and MCP-4 in acute and chronic lesions, suggesting that these chemotactic factors play a major role in the pathophysiologic mechanisms of AD. | 10808183 | 2000 | ||||
|
0.350 | AlteredExpression | disease | BEFREE | Immunoreactivity and transcripts of eotaxin and CCR3 were significantly increased in lesional skin from atopic dermatitis, but not in nonatopic controls. | 10417617 | 1999 |