Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
0.350 AlteredExpression disease BEFREE There was a clear pattern of overall suppression of the mediators, especially those noted for their pro-inflammatory role in AD (monocyte chemoattractant protein [MCP]-1, regulated on activation, normal T cell expressed and secreted, cutaneous T-cell-attracting chemokine, Eotaxin, and macrophage inflammatory protein-1α, etc.). 29853747 2018
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
0.350 Biomarker disease LHGDN To investigate whether single-nucleotide polymorphisms of the eotaxin gene are associated with AD, we investigated the genotype and allelic frequencies of -426C-->T, -384A-->G, and 67G-->A SNPs in 130 Italian families. 18312459 2008
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
0.350 Biomarker disease CTD_human Peroxisome proliferator-activated receptor alpha regulates skin inflammation and humoral response in atopic dermatitis. 18249437 2008
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
0.350 GeneticVariation disease BEFREE To investigate whether single-nucleotide polymorphisms of the eotaxin gene are associated with AD, we investigated the genotype and allelic frequencies of -426C-->T, -384A-->G, and 67G-->A SNPs in 130 Italian families. 18312459 2008
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
0.350 GeneticVariation disease BEFREE Eotaxin gene SNPs in the promoter and exon regions are not associated with susceptibility to AD, but two of them in the promoter region are associated with phenotype of AD. 12234713 2002
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
0.350 AlteredExpression disease BEFREE There is an increased expression of eotaxin and MCP-4 in acute and chronic lesions, suggesting that these chemotactic factors play a major role in the pathophysiologic mechanisms of AD. 10808183 2000
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
0.350 AlteredExpression disease BEFREE Immunoreactivity and transcripts of eotaxin and CCR3 were significantly increased in lesional skin from atopic dermatitis, but not in nonatopic controls. 10417617 1999