Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2313
Gene Symbol: FLI1
FLI1
0.050 Biomarker disease BEFREE Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma. 28232470 2017
Entrez Id: 2313
Gene Symbol: FLI1
FLI1
0.050 Biomarker disease BEFREE Thus, blocking the TGFβ/c-Abl/PKCδ/phospho-Fli-1 pathway could be an attractive alternative approach to therapy for scleroderma. 21321929 2011
Entrez Id: 2313
Gene Symbol: FLI1
FLI1
0.050 Biomarker disease BEFREE Endothelial Fli1 deficiency impairs vascular homeostasis: a role in scleroderma vasculopathy. 20228226 2010
Entrez Id: 2313
Gene Symbol: FLI1
FLI1
0.050 PosttranslationalModification disease BEFREE Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts. 16802366 2006
Entrez Id: 2313
Gene Symbol: FLI1
FLI1
0.050 Biomarker disease BEFREE In contrast to healthy skin, Fli1 protein is consistently absent from fibroblasts and significantly reduced in endothelial cells in clinically involved scleroderma skin, which correlates with enhanced collagen synthesis in systemic sclerosis skin. 12875977 2003