Gene: HLA-DRB1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.080 GeneticVariation disease BEFREE Association of the HLA-DRB1 with scleroderma in Chinese population. 25184637 2014
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.080 GeneticVariation disease BEFREE Furthermore, FLEDR is always carried by the most abundantly expressed ß chain: ß1 in HLA DRB1*11 haplotypes and ß5 in HLA-DRB1*15 haplotypes.In French Caucasian patients with SSc, FLEDR is the main presenting motif influencing ATA production in dcSSc. 22615829 2012
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.080 Biomarker disease BEFREE Complete HLA-DRB1 typing was obtained for 58 SSc and 68 control families (proband/children). 19208687 2009
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.080 GeneticVariation disease BEFREE The frequency of the HLA-DRB1*03-DQA1*05-DQB1*02 haplotype was significantly increased in the JDM-SSc (P = 0.003) and anti-PM-Scl antibody (P = 0.002) positive groups. 18003662 2007
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.080 Biomarker disease BEFREE HLA-DRB1*01 and HLA-DRB1*11 were associated with susceptibility to scleroderma, whereas HLA-DRB1*07 was protective. 16078323 2005
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.080 GeneticVariation disease BEFREE An Amerindian HLA DR2 haplotype (DRB1*1602) was significantly associated with scleroderma in this population in a previous study. 10082433 1999
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.080 Biomarker disease BEFREE These data support the role of DR5 (DRB1*1104) in the genetic susceptibility to develop scleroderma in Mexican patients and also sustain the notion of genetically determined clinical subgroups of SSc. 7774089 1995
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.080 GeneticVariation disease BEFREE This would suggest that the DRB1 locus may well be the primary disease promoting locus in scleroderma. 2101346 1991