Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.050 Biomarker disease BEFREE Tocilizumab is an IL-6 receptor antagonist established as safe and effective, primarily in rheumatoid arthritis, and has shown promise in scleroderma. 28956500 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.050 Biomarker disease BEFREE A bleomycin-induced scleroderma model was induced in mice with a B cell-specific deficiency in IL-6 or IL-10. 30009261 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.050 AlteredExpression disease BEFREE Scleroderma Peripheral B Lymphocytes Secrete Interleukin-6 and Transforming Growth Factor β and Activate Fibroblasts. 27992693 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.050 AlteredExpression disease BEFREE Establishment and characterization of a human B cell line from the lung tissue of a patient with scleroderma; extraordinary high level of IL-6 secretion by stimulated fibroblasts. 11237429 2001
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.050 Biomarker disease BEFREE Interleukin-6 (IL-6) is an important immunoregulatory cytokine that has been implicated in a number of fibrotic autoimmune diseases such as scleroderma, interstitial nephritis, and pulmonary interstitial fibrosis. 10720455 2000