|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
Outcomes were also assessed in patients with diabetes and/or hyperglycemia (impaired glucose tolerance [IGT] and diabetes population [IGT-diabetes population]) and all patients included in the 3 studies (intention-to-treat [ITT] population).
|
30025392 |
2019 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
The prevalence in gestational diabetes of these autoimmune markers of type 1 diabetes (T1D) has been assessed in many studies, together with the risk of progression of AABs-positive GDM towards impaired glucose regulation (IFG or IGT) and overt diabetes after pregancy.
|
31053128 |
2019 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
We then found that circulating CILP-2 levels had a progressive increase from normal to IGT (a pre-diabetic status) and then to diabetes, which was correlated positively with WHR, triglyceride, FBG, 2-h blood glucose after glucose overload (2h-BG), HbA1c, FIns, 2h-Ins, and HOMA-IR but negatively with HDL-C. CILP-2 expression was increased in the liver and muscle but decreased in adipose tissues of obese mice or T2DM patients.
|
30896018 |
2019 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
The HRQOL-15D scores of 172 people with pre-diabetes (108 with Impaired Fasting Glucose [IFG], 64 with Impaired Glucose Tolerance [IGT], aged 58.3 ± 10.3 years) and 198 with NGT (aged 54.4 ± 10.1 years) from the Greek part of the DEPLAN study (Diabetes in Europe - Prevention using Lifestyle, Physical Activity and Nutritional Intervention), were compared to 100 diabetes patients' scores (aged 60.9 ± 12.5 years, diabetes duration 17.0 ± 10.0 years, HbA1c 7.2 ± 1.2%), derived from the outpatient Diabetes Clinic of a University Hospital.
|
29843700 |
2018 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
A correlation relationship between leukocyte telomere length and 2-h post-load plasma glucose level in NGT; IFG/IGT and DM groups ( P = 0.027; 0.029 and 0.049, respectively) was revealed; the association between leukocyte telomere length and fasting plasma glucose was confirmed in DM group only ( P = 0.009).
|
28299976 |
2017 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
RHR levels were significantly higher in the subjects with isolated impaired fasting glucose (i-IFG), isolated impaired glucose tolerance (i-IGT), IFG + IGT and diabetes than in those with normal glucose regulation.
|
28903724 |
2017 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
Lifestyle interventions significantly improved FPG, HbA1c, FI, HOMA-IR, and bodyweight among adults without IGT or diabetes, and might reduce progression of hyperglycemia to type 2 diabetes mellitus.
|
28024276 |
2017 |
|
LOC102723407
|
0.100 |
GeneticVariation
|
group |
BEFREE |
An OGTT with measurement of glucose, insulin and C-peptide was performed in HNF4A participants with diabetes mellitus (DM) (n = 14), HNF4A-IGT (n = 7) and age- and BMI-matched MODY negative family members (n = 10).
|
27552834 |
2016 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
Lowering the threshold to 5.6 mmol/l raised the population-attributable risk of IFG to 23% (95% CI: 20-25); its contribution to diabetes progression, however, was largely due to co-existent IGT.
|
19224196 |
2009 |
|
LOC102723407
|
0.100 |
AlteredExpression
|
group |
BEFREE |
A total of 717 overweight/obese individuals underwent oral glucose tolerance test and were stratified in four groups according to fasting and 2 h glucose levels (NGT, IGT, CGI, T2DM), representing the natural history of diabetes from normal glucose tolerance to overt disease.
|
17912268 |
2008 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
Study I (the DPS) included 507 individuals with IGT who were randomly allocated to control and intervention groups and followed for an average of 3.9 years to monitor for progression to diabetes.
|
17437080 |
2007 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
IFG and IGT identified in general practice during a stepwise, high-risk screening programme for type 2 diabetes have high 1-year progression rates to diabetes.
|
17143605 |
2007 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
A total of 52% of subjects in the relatives' group showed an abnormal oral glucose tolerance (either as impaired glucose tolerance [IGT] or diabetes) and had more features of the insulin resistance syndrome, despite showing similar body composition as controls.
|
12898475 |
2003 |
|
LOC102723407
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Of the case subjects, 23% were glucose intolerant (4% with diabetes and 19% with impaired glucose tolerance [IGT]) compared with 6.5% (all with IGT) of control subjects (P = 0.02).
|
11128348 |
2000 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
Diabetes was detected in 2/28 (7.1%) and 3/31 (9.7%) and IGT was detected in 5/28 (25%) and 8/31 (25%) of groups 1 and 2, respectively.
|
9371478 |
1997 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
In conclusion, this study has demonstrated that in South-African Indians with IGT, the majority (50.4%) progress to NIDDM within 4 yr; significant predictors of subsequent diabetes are the baseline fasting and 2-h plasma glucose concentration.(ABSTRACT TRUNCATED AT 250 WORDS)
|
8454106 |
1993 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
Seven probands had neither parent affected with diabetes or IGT, 10 had one parent affected (6 with diabetes and 4 with IGT), and 3 had both parents affected.
|
8420807 |
1993 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
We compared the prevalence of NIDDM and IGT for 4914 subjects according to their parental history of diabetes (mother only, father only, both parents, neither parent).
|
8404430 |
1993 |
|
LOC102723407
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The overall rates were 7.6 and 7.8% for diabetes and IGT, respectively.
|
1468278 |
1992 |
|
LOC102723407
|
0.100 |
Biomarker
|
group |
BEFREE |
Among them 10 (15.6%) had developed diabetes, 19 (29.7%) had developed IGT and the remaining 35 (54.7%) had maintained normal GTT.
|
2187663 |
1990 |