| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | disease | BEFREE | Vitiligo was significantly associated with single-nucleotide polymorphisms (SNPs) in a 30-kb LD block on chromosome 6q27, in close vicinity to IDDM8, a linkage and association signal for type I diabetes mellitus and rheumatoid arthritis. | 19890347 | 2010 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | The IDDM8 region on chromosome 6q27, first identified as a susceptibility locus for type 1 diabetes, has previously been linked and associated with rheumatoid arthritis (RA). | 16945141 | 2006 | ||||
|
0.070 | Biomarker | disease | BEFREE | These findings suggest that the PDCD2 gene is a likely susceptibility gene for T1D within IDDM8. | 15848047 | 2005 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | A microsatellite marker allele and multiple haplotypes were associated with IDDM8, which suggests localization of this type 1 diabetes susceptibility gene to the terminal 200 kb of chromosome 6. | 10868976 | 2000 | ||||
|
0.070 | Biomarker | disease | BEFREE | We could not confirm linkage for IDDM5, IDDM8 and IDDM15 in our population, possibly due to population-specific differences in genetic susceptibility and/or environmental triggering factors to type 1 diabetes. | 11204251 | 2000 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | We developed a statistical method to test this hypothesis in a panel of 523 multiplex families from France, the United States, and Denmark (a total of 667 affected sib pairs, 536 with both parents genotyped), and here present evidence (P = .00003) of a susceptibility locus for IDDM located 32 cM from HLA in males but not linked to HLA in females and distinct from IDDM5 and IDDM8. | 8981961 | 1997 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Linkage analysis of type 1 diabetes sib pair families (n = 334) has suggested two separate regions of human chromosome 6q are linked to disease (designated IDDM5 and IDDM8). | 8817350 | 1996 |