×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
GeneticVariation
disease
BEFREE
Initial results showed modest methylation differences between discordant MZ twins for the MHC region and T1D -associated CpG sites, BACH2 , INS-IGF2, and CLEC16A (DNAm difference range: 2.2%-5.0%).
26782299
2016
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
GeneticVariation
disease
GWASCAT
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.
25751624
2015
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
Biomarker
disease
BEFREE
The present findings suggest that the type 1 diabetes candidate gene BACH2 regulates proinflammatory cytokine-induced apoptotic pathways in pancreatic β-cells by crosstalk with another candidate gene, PTPN2, and activation of JNK1 and BIM.
24608439
2014
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
GeneticVariation
disease
BEFREE
Genetic polymorphisms within a single locus encoding the transcription factor BACH2 are associated with numerous autoimmune and allergic diseases including asthma, Crohn's disease, coeliac disease, vitiligo, multiple sclerosis and type 1 diabetes .
23728300
2013
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
GeneticVariation
disease
GWASCAT
Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.
21829393
2011
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
GeneticVariation
disease
GWASDB
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.
21980299
2011
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
GeneticVariation
disease
GWASDB
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
19430480
2009
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
GeneticVariation
disease
GWASCAT
Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.
18840781
2009
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
GeneticVariation
disease
GWASDB
Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.
18840781
2009
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
GeneticVariation
disease
GWASCAT
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
19430480
2009
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
Biomarker
disease
CTD_human
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.
18978792
2008
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
GeneticVariation
disease
GWASCAT
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.
18978792
2008
×
Entrez Id:
60468
Gene Symbol:
BACH2
BACH2
0.430
GeneticVariation
disease
GWASDB
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.
18978792
2008