Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE This randomized, placebo-controlled trial was performed for 8 weeks to investigate the potential effects of astaxanthin (AST) supplementation on the adiponectin concentration, lipid peroxidation, glycemic control, insulin sensitivity, and anthropometric indices in participants with type 2 diabetes mellitus. 29384321 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE Recent studies indicate a paradoxical relationship between adiponectin and cardiovascular mortality across many clinical settings including type 2 diabetes. 31805941 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 GeneticVariation disease BEFREE This study demonstrated some association of 276T allele and ADIPOQ gene G276T heterozygous genotype as well as KCNJ11 gene 23Lys allele with T2D in ethnic Kyrgyz, but study results should be interpreted with caution because of the limited statistical power. 30467975 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE CTRP3 was independently associated with HOMA-IR (r = -0.327, p < 0.05) and adiponectin (r = 0.436, p < 0.01) in T2DM group. 31009504 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE The effects of curcumin supplementation on high-sensitivity C-reactive protein, serum adiponectin, and lipid profile in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled trial. 30864188 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE In this review, we not only discuss the favorable adipokines like adiponectin, omentin, C1q tumor necrosis factor-related proteins, but also unfavorable ones like resisitin and visfatin, in the aim of finding potential biomarkers recommended for the clinical use in the diagnosis, prognosis and follow up of patients with T2D at high risk of developing cardiovascular diseases as well as leading to new therapeutic approaches. 31229411 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE The aim of this study was to investigate the effect of zinc supplementation on glycemic control, and the potential mediating role of adiponectin, in patients with type 2 diabetes. 31345359 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 GeneticVariation disease BEFREE The goal of the study was to assess associations of rs17300539, rs266729, rs182052, rs2241766, and rs17366743 single nucleotide polymorphisms (SNPs) of the <i>ADIPOQ</i> gene with concentrations of serum adiponectin and with coronary atherosclerosis and type 2 diabetes mellitus in 447 patients (316 men and 131 women) subjected to coronary angiography. 31561637 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 AlteredExpression disease BEFREE Patients diagnosed with type-2 diabetes (T2D) and obesity exhibit low adiponectin concentration levels in their blood. 30678182 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE The aim of this pilot study was to explore relations between biomarkers of Cd, Pb and Hg exposure, early urinary biomarkers of renal dysfunction (kidney-injured molecule-1 (KIM-1), N-acetylglucosaminidase and retinol-binding protein (RBP)) and plasma biomarkers deemed predictive of the risk of developing T2D (adiponectin, leptin, branched-chain and aromatic amino acids), among 70 participants (age range: (46-87 yrs)) from the Canadian Longitudinal Study on Aging (CLSA) with normal glycemic control (glycated haemoglobin ≤ 6.5%) in all but four of them. 31100493 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE Association of Low Serum Adiponectin Levels with Aortic Arterial Stiffness in Patients with Type 2 Diabetes. 31234308 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 GeneticVariation disease BEFREE The aim of this study was to investigate the associations between the TCF7L2 rs7903146 polymorphism, adiponectin levels, age at onset of obesity and the occurrence of type 2 diabetes (T2D) in a sample of obese Polish adults. 30899283 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE Patients with T1D had a lower waist/hip ratio and serum triglycerides but higher serum adiponectin than patients with T2D. 30689904 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE We explored the effects of Roux-en-Y gastric bypass (RYGB) on the circulating levels of adiponectin, leptin, and the adiponectin/leptin (Adpn/Lep) ratio in patients with obesity and type 2 diabetes (T2D). 31484347 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 GeneticVariation disease BEFREE Leptin/adiponectin imbalance is associated with increased risk of developing obesity and type 2 diabetes mellitus. 30841005 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE In TNFi-treated patients, leptin and resistin significantly increased, whereas no difference was found analyzing adiponectin and adipsin, during the follow-up.Our data may suggest a beneficial effect of IL-1 inhibition on measures of metabolic derangement in RA-associated T2D. 30762811 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE The Effects of Adiponectin and Adiponectin Receptor 1 Levels on Macrovascular Complications Among Patients with Type 2 Diabetes Mellitus. 30816670 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 AlteredExpression disease BEFREE Patients with T2D have significantly higher levels of A-FABP and lower levels of adiponectin. 29717906 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE The electronic databases, without regard to language restrictions including PubMed/Medline, Google Scholar, SCOPUS and ISI Web of Science until August 2017, were used to identify randomized controlled trials that assessed the effect of n-3 PUFAs on serum leptin and adiponectin concentrations in type 2 diabetes. 29453672 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE Therefore, we investigated the association of these adiponectin-related parameters with T2D. 29494595 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 GeneticVariation disease BEFREE Our findings suggest that the adiponectin 45T/G polymorphism is associated with diabetic cardiovascular complication in type 2 diabetes. 29686595 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 AlteredExpression disease BEFREE Adiponectin levels were 59% higher in the NGT group than those in the IGT/T2DM group (<i>P</i> < 0.01). 29951553 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 Biomarker disease BEFREE It was therefore quite unexpected that large prospective human studies suggested that adiponectin is simply a marker of glucose homeostasis, with no direct favorable effect on the risk of type 2 diabetes and cardiovascular disease. 29263167 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 AlteredExpression disease BEFREE This study evaluated if the performance in cognitive tests was associated with adiponectin levels prior the development of type 2 diabetes in middle-aged individuals. 30002734 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.600 AlteredExpression disease BEFREE This observational cohort study suggested that blood adiponectin levels are not related to further cardiovascular events in patients with type 2 diabetes. 30160532 2018