|
CDKN2B-AS1
|
0.180 |
AlteredExpression
|
disease |
BEFREE |
ANRIL was upregulated in peripheral venous blood from patients with T2DM-MI and in myocardial tissues from the established T2DM-MI model mice.
|
31469688 |
2019 |
|
CDKN2B-AS1
|
0.180 |
AlteredExpression
|
disease |
BEFREE |
Reduced mRNA levels of CDKN2A (p16<sup>Ink4a</sup>), CDKN2B (p15<sup>Ink4b</sup>), and CDKN2BAS were observed in human T2DM and T2DM-CAD subjects compared with controls.
|
30176239 |
2019 |
|
CDKN2B-AS1
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
Variants in the long noncoding RNA (lncRNA) gene CDKN2B-AS1 (CDKN2B antisense RNA 1; ANRIL) are genome-wide associated with type 2 diabetes (T2D), atherosclerosis, and several forms of cancer.
|
30108282 |
2019 |
|
CDKN2B-AS1
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
However, we identified pleiotropic genetic variations for depressive symptoms and T2D (in the IGF2BP2, CDKAL1, CDKN2B-AS, and PLEKHA1 genes), and fasting glucose (in the MADD, CDKN2B-AS, PEX16, and MTNR1B genes).
|
29280852 |
2018 |
|
CDKN2B-AS1
|
0.180 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
|
30054458 |
2018 |
|
CDKN2B-AS1
|
0.180 |
AlteredExpression
|
disease |
BEFREE |
The aim of the present study was to compare the expression level of ANRIL between T2DM patients with and without CAD.
|
29308617 |
2018 |
|
CDKN2B-AS1
|
0.180 |
GeneticVariation
|
disease |
GWASCAT |
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
|
28869590 |
2017 |
|
CDKN2B-AS1
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
The lncRNA ANRIL is located at a genetic susceptibility locus for coronary artery diseases and type 2 diabetes.
|
28122089 |
2017 |
|
CDKN2B-AS1
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
In the discovery stage, an Asian-specific coding variant rs2233580 (p.Arg192His) in PAX4, and two variants at the known loci, CDKN2B-AS1 and KCNQ1, were significantly associated with type 2 diabetes with exome-wide significance (p <sub>discovery</sub> < 6.45 × 10<sup>-7</sup>).
|
27744525 |
2017 |
|
CDKN2B-AS1
|
0.180 |
GeneticVariation
|
disease |
GWASDB |
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
|
22885922 |
2012 |
|
CDKN2B-AS1
|
0.180 |
GeneticVariation
|
disease |
BEFREE |
While the exact role of ANRIL awaited further elucidation, common disease genomewide association studies (GWAS) have surprisingly identified the ANRIL gene as a genetic susceptibility locus shared associated by coronary disease, intracranial aneurysm and also type 2 diabetes.
|
20956613 |
2011 |
|
CDKN2B-AS1
|
0.180 |
GeneticVariation
|
disease |
GWASDB |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
|
17463249 |
2007 |
|
CDKN2B-AS1
|
0.180 |
GeneticVariation
|
disease |
GWASCAT |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
|
17463249 |
2007 |