Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.080 | GeneticVariation | disease | BEFREE | At the NIDDM1 locus (2q37.3), calpain-10 (CAPN10) encodes for a ubiquitously expressed protease implicated in the two fundamental pathophysiological aspects of T2DM. | 18487065 | 2008 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | A positional cloning study of type 2 diabetes in Mexican Americans identified a region, termed "NIDDM1," on chromosome 2q37 with significant linkage evidence. | 15696418 | 2005 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The 2q34-37 region lies close to the type 2 diabetes NIDDM1 locus. | 12947017 | 2003 | ||||
|
0.080 | Biomarker | disease | BEFREE | Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians. | 12453914 | 2002 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | We found some evidence for linkage of T2DM to chromosome 2q approximately 20 cM proximal to the NIDDM1/CAPN10 locus. | 11836299 | 2002 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Here we describe the positional cloning of a gene located in the NIDDM1 region that shows association with type 2 diabetes in Mexican Americans and a Northern European population from the Botnia region of Finland. | 11017071 | 2000 | ||||
|
0.080 | Biomarker | disease | BEFREE | Using this method, we show that the interaction of genes on chromosomes 2 (NIDDM1) and 15 (near CYP19) makes a contribution to susceptibility to type 2 diabetes in Mexican Americans from Starr County, Texas. | 9988276 | 1999 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | In the first reported positive result from a genome scan for non-insulin-dependent diabetes mellitus (NIDDM), Hanis et al. found significant evidence of linkage for NIDDM on chromosome 2q37 and named the putative disease locus NIDDM1 (Hanis et al.1996.Nat.Genet.13:161-166). | 9710438 | 1998 |