| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | The same chromosome region entails at least a major risk gene for type 2 diabetes (T2D) within NIDDM2, the non-insulin-dependent-diabetes 2 locus. | 21496327 | 2011 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Type 2 diabetes has a replicated linkage on chromosome12q24.2 (NIDDM2 locus/non-insulin-dependent diabetes mellitus 2 locus), near the HNF-1alpha/MODY3 gene. | 20069546 | 2010 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | PSMD9 gene variants within NIDDM2 may rarely contribute to type 2 diabetes. | 17516568 | 2007 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The gene for MODY3 diabetes, HNF1alpha, lies in a region that has shown linkage to late-onset type 2 diabetes (12q24, NIDDM2), and previous association studies have suggested a weak trend toward association for common missense variants in HNF1alpha with glucose-related traits. | 16046299 | 2005 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Evidence from a large U.K. family collection that genes influencing age of onset of type 2 diabetes map to chromosome 12p and to the MODY3/NIDDM2 locus on 12q24. | 14988275 | 2004 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Rather, they strongly suggest that a previously undetected type 2 diabetes locus exists 50 cM from NIDDM2 on 12q. | 10535461 | 1999 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Taken together with our recent findings of linkage between this region on chromosome 12 and an insulin-deficient form of NIDDM (NIDDM2), the data suggest that mutations at the MODY3/NIDDM2 gene(s) result in a reduced insulin secretory response, that subsequently progresses to diabetes and underlines the importance of subphenotypic classification in studies of diabetes. | 9045858 | 1997 | ||||
|
0.080 | Biomarker | disease | BEFREE | We infer the existence of a gene NIDDM2 causing NIDDM associated with low insulin secretion, and suggest that NIDDM2 and MODY3 may represent different alleles of the same gene. | 8782826 | 1996 |