Gene: GH1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2688
Gene Symbol: GH1
GH1 		0.060 Biomarker disease BEFREE However, the exact mechanism and the downstream pathways by which excess GH leads to diabetic nephropathy is not established. 31511328 2019
Entrez Id: 2688
Gene Symbol: GH1
GH1 		0.060 Biomarker disease BEFREE In this review, we summarize recent advances that shed light on actions of GH on the podocyte that could play a role in the pathogenesis of DN. 28748185 2017
Entrez Id: 2688
Gene Symbol: GH1
GH1 		0.060 Biomarker disease BEFREE Therefore, we conclude that the GH-dependent increase in TGFBIp in the podocyte is one of the mechanisms responsible for podocyte depletion in DN. 25740786 2015
Entrez Id: 2688
Gene Symbol: GH1
GH1 		0.060 AlteredExpression disease BEFREE We speculate that the actions of GH on ZEB2 and P- and E-cadherin expression play a role in the pathogenesis of microalbuminuria of DN. 20682777 2010
Entrez Id: 2688
Gene Symbol: GH1
GH1 		0.060 Biomarker disease BEFREE In particular, growth hormone (GH) and insulin-like growth factors (IGFs) have a long history in diabetes, with measurable effects on the development of diabetic kidney disease in experimental animal models through changes in a complex intrarenal system. 11527082 2001
Entrez Id: 2688
Gene Symbol: GH1
GH1 		0.060 Biomarker disease BEFREE These results suggest that growth hormone is playing a role in diabetic nephropathy, and elevated levels of growth hormone can directly affect the kidneys independent of the levels of glucose and glycated hemoglobin. 8895392 1996