Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 695
Gene Symbol: BTK
BTK
0.010 Biomarker phenotype BEFREE <i>Drosophila</i> Bruton's Tyrosine Kinase Regulates Habituation Latency and Facilitation in Distinct Mushroom Body Neurons. 31530645 2019
Entrez Id: 1385
Gene Symbol: CREB1
CREB1
0.010 AlteredExpression phenotype BEFREE Habituation training increased CaMKII and CREB activity but had no effect on CaMKIV and ERK1/2 activity in the CA1, while inhibition of CaMKII but not ERK1/2 impaired "internal model" retention. 28230177 2017
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
0.020 GeneticVariation phenotype BEFREE 5-HT(2A)R A-1438G and T102C genotype explained approximately 11% of the PPI and early habituation variance. 18420180 2008
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.350 GeneticVariation phenotype BEFREE 5-HTTLPR genotype influences amygdala habituation to sad faces differently for individuals with ASD vs controls. 23526151 2014
Entrez Id: 116369
Gene Symbol: SLC26A8
SLC26A8
0.010 Biomarker phenotype BEFREE Tat1-86 induced developmental neurotoxic effects, as witnessed by delays in eye opening, delays in early reflex development and alterations in prepulse inhibition (PPI) and between-session habituation of locomotor activity. 25285887 2014
Entrez Id: 117247
Gene Symbol: SLC16A10
SLC16A10
0.010 Biomarker phenotype BEFREE Tat1-86 induced developmental neurotoxic effects, as witnessed by delays in eye opening, delays in early reflex development and alterations in prepulse inhibition (PPI) and between-session habituation of locomotor activity. 25285887 2014
Entrez Id: 11343
Gene Symbol: MGLL
MGLL
0.010 GeneticVariation phenotype BEFREE Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis. 26595473 2015
Entrez Id: 414
Gene Symbol: ARSD
ARSD
0.010 Biomarker phenotype BEFREE ASD children presented a reduced habituation in the P1 component and a decrease in the amplitude of the mismatch negativity indicating a lower auditory discrimination with respect to controls. 31728809 2020
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
0.310 Biomarker phenotype CTD_human A missense mutation in human fatty acid amide hydrolase associated with problem drug use. 12060782 2002
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
0.010 GeneticVariation phenotype BEFREE According to this practical and scientific demand, we aimed to investigate the relationship between seven top-ranked variants in the SZgene database [120-bpTR in DRD4, rs1801028 and rs6277 in DRD2, rs1019385 (T200G) in GRIN2B, rs1800532 in TPH1, rs1801133 (C677T) in MTHFR, rs2619528 (P1765) in DTNBP1] and prepulse inhibition (PPI) and habituation after acoustic stimulus (HAB). 20421849 2010
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.310 GeneticVariation phenotype BEFREE According to this practical and scientific demand, we aimed to investigate the relationship between seven top-ranked variants in the SZgene database [120-bpTR in DRD4, rs1801028 and rs6277 in DRD2, rs1019385 (T200G) in GRIN2B, rs1800532 in TPH1, rs1801133 (C677T) in MTHFR, rs2619528 (P1765) in DTNBP1] and prepulse inhibition (PPI) and habituation after acoustic stimulus (HAB). 20421849 2010
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.020 GeneticVariation phenotype BEFREE According to this practical and scientific demand, we aimed to investigate the relationship between seven top-ranked variants in the SZgene database [120-bpTR in DRD4, rs1801028 and rs6277 in DRD2, rs1019385 (T200G) in GRIN2B, rs1800532 in TPH1, rs1801133 (C677T) in MTHFR, rs2619528 (P1765) in DTNBP1] and prepulse inhibition (PPI) and habituation after acoustic stimulus (HAB). 20421849 2010
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
0.020 GeneticVariation phenotype BEFREE According to this practical and scientific demand, we aimed to investigate the relationship between seven top-ranked variants in the SZgene database [120-bpTR in DRD4, rs1801028 and rs6277 in DRD2, rs1019385 (T200G) in GRIN2B, rs1800532 in TPH1, rs1801133 (C677T) in MTHFR, rs2619528 (P1765) in DTNBP1] and prepulse inhibition (PPI) and habituation after acoustic stimulus (HAB). 20421849 2010
Entrez Id: 84062
Gene Symbol: DTNBP1
DTNBP1
0.020 GeneticVariation phenotype BEFREE According to this practical and scientific demand, we aimed to investigate the relationship between seven top-ranked variants in the SZgene database [120-bpTR in DRD4, rs1801028 and rs6277 in DRD2, rs1019385 (T200G) in GRIN2B, rs1800532 in TPH1, rs1801133 (C677T) in MTHFR, rs2619528 (P1765) in DTNBP1] and prepulse inhibition (PPI) and habituation after acoustic stimulus (HAB). 20421849 2010
Entrez Id: 7166
Gene Symbol: TPH1
TPH1
0.020 GeneticVariation phenotype BEFREE According to this practical and scientific demand, we aimed to investigate the relationship between seven top-ranked variants in the SZgene database [120-bpTR in DRD4, rs1801028 and rs6277 in DRD2, rs1019385 (T200G) in GRIN2B, rs1800532 in TPH1, rs1801133 (C677T) in MTHFR, rs2619528 (P1765) in DTNBP1] and prepulse inhibition (PPI) and habituation after acoustic stimulus (HAB). 20421849 2010
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.030 Biomarker phenotype BEFREE All genes increased in response to initial stress (IL-6: F=3.8; p=0.029; IL-1β: F=7.1; p=0.008; NF-κB: F=5.1; p=0.009; IκB: F=4.7; p=0.013) and showed habituation to repeated stress (IL-6: t=2.3; p=0.03; IL-1β: t=3.9; p=0.001; NF-κB: t=2.1; p=0.041; IκB: t=3.1; p=0.005). 25683696 2015
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.020 Biomarker phenotype BEFREE All genes increased in response to initial stress (IL-6: F=3.8; p=0.029; IL-1β: F=7.1; p=0.008; NF-κB: F=5.1; p=0.009; IκB: F=4.7; p=0.013) and showed habituation to repeated stress (IL-6: t=2.3; p=0.03; IL-1β: t=3.9; p=0.001; NF-κB: t=2.1; p=0.041; IκB: t=3.1; p=0.005). 25683696 2015
Entrez Id: 1129
Gene Symbol: CHRM2
CHRM2
0.300 Biomarker phenotype CTD_human Altered neural cholinergic receptor systems in cocaine-addicted subjects. 20393457 2010
Entrez Id: 348
Gene Symbol: APOE
APOE
0.010 Biomarker phenotype BEFREE Although motivated behavior is influenced by many processes, hyper-excitability of ApoE4 mice may contribute to impaired odor habituation, while hypo-excitability of ApoE2 mice may contribute to its protective effects. 29678753 2018
Entrez Id: 3778
Gene Symbol: KCNMA1
KCNMA1
0.010 PosttranslationalModification phenotype BEFREE Although results using different approaches do not always perfectly align, together they provide convincing evidence for a crucial role of BK channel phosphorylation in synaptic depression underlying short-term habituation of startle. 28348135 2017
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
0.300 Biomarker phenotype CTD_human Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential. 21513772 2011
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.300 Biomarker phenotype CTD_human Association between gene polymorphisms of SLC22A3 and methamphetamine use disorder. 17010131 2006
Entrez Id: 4791
Gene Symbol: NFKB2
NFKB2
0.010 Biomarker phenotype BEFREE Based on the PRVEP findings, it may be concluded that migraineurs have sensitization of P100 and impaired habituation of N75 especially during headache. 28974100 2018
Entrez Id: 6490
Gene Symbol: PMEL
PMEL
0.010 Biomarker phenotype BEFREE Based on the PRVEP findings, it may be concluded that migraineurs have sensitization of P100 and impaired habituation of N75 especially during headache. 28974100 2018
Entrez Id: 4940
Gene Symbol: OAS3
OAS3
0.010 Biomarker phenotype BEFREE Based on the PRVEP findings, it may be concluded that migraineurs have sensitization of P100 and impaired habituation of N75 especially during headache. 28974100 2018