Gene: NLRP3 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.040 Biomarker disease BEFREE Polydatin Inhibits NLRP3 Inflammasome in Dry Eye Disease by Attenuating Oxidative Stress and Inhibiting the NF-κB Pathway. 31731792 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.040 AlteredExpression disease BEFREE Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye. 28238526 2017
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.040 Biomarker disease BEFREE Hence in this study we determine whether: a) ROS activated NLRP3 inflammasomes mediate hyperosmotic stress-induced inflammation in human corneal epithelial cells (HCECs); b) the ROS-NLRP3-IL-1β axis activation is associated with environment-induced DE. 25701684 2015
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.040 Biomarker disease BEFREE These observations suggest the involvement of NLRP3 inflammasome in the onset and development of the inflammation in dry eye. 25962072 2015