Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 43
Gene Symbol: ACHE
ACHE
0.010 Biomarker disease BEFREE Severe autonomic dysfunction like reduced cardiac catecholamine-containing or acetylcholinesterase-positive innervation have been reported in CD. 31788770 2020
Entrez Id: 4477
Gene Symbol: MSMB
MSMB
0.010 Biomarker disease BEFREE Subsequently, the diagnosis was changed to PSP due to hypometric downward gaze, reduced blink frequency, symmetric bradykinesia, rigidity, and the absence of autonomic dysfunction. 31216016 2019
Entrez Id: 6462
Gene Symbol: SHBG
SHBG
0.010 Biomarker disease BEFREE Conclusions Daytime SD of SBP is a better screening tool than nondipping status in detecting autonomic dysfunction. 30905258 2019
Entrez Id: 5723
Gene Symbol: PSPH
PSPH
0.010 Biomarker disease BEFREE Subsequently, the diagnosis was changed to PSP due to hypometric downward gaze, reduced blink frequency, symmetric bradykinesia, rigidity, and the absence of autonomic dysfunction. 31216016 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.010 AlteredExpression disease BEFREE The aim of this study was to determine whether ADAM17 modulates presympathetic neuronal activity to promote autonomic dysregulation in salt-sensitive hypertension. 31006330 2019
Entrez Id: 57091
Gene Symbol: CASS4
CASS4
0.010 Biomarker disease BEFREE Seventy-five patients with de novo PD underwent a comprehensive autonomic function test and were classified into 2 groups according to the Composite Autonomic Severity Score (CASS; 30 with moderate to severe autonomic dysfunction [CASS 4-10, PD-AUT+] and 45 without significant autonomic dysfunction [CASS 0-3, PD-AUT-]). 30796135 2019
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
0.010 Biomarker disease BEFREE <b>NEW & NOTEWORTHY</b> PRR knockdown in PVN neurons attenuates the development of DOCA-salt hypertension and autonomic dysfunction through a decrease in ERK1/2 activation in the PVN and RVLM during hypertension. 30925093 2019
Entrez Id: 6814
Gene Symbol: STXBP3
STXBP3
0.010 Biomarker disease BEFREE Subsequently, the diagnosis was changed to PSP due to hypometric downward gaze, reduced blink frequency, symmetric bradykinesia, rigidity, and the absence of autonomic dysfunction. 31216016 2019
Entrez Id: 10247
Gene Symbol: RIDA
RIDA
0.010 Biomarker disease BEFREE Subsequently, the diagnosis was changed to PSP due to hypometric downward gaze, reduced blink frequency, symmetric bradykinesia, rigidity, and the absence of autonomic dysfunction. 31216016 2019
Entrez Id: 140683
Gene Symbol: BPIFA2
BPIFA2
0.010 Biomarker disease BEFREE Subsequently, the diagnosis was changed to PSP due to hypometric downward gaze, reduced blink frequency, symmetric bradykinesia, rigidity, and the absence of autonomic dysfunction. 31216016 2019
Entrez Id: 10267
Gene Symbol: RAMP1
RAMP1
0.010 Biomarker disease BEFREE Increased receptor activity-modifying protein 1 in the nervous system is sufficient to protect against autonomic dysregulation and hypertension. 29297736 2019
Entrez Id: 5818
Gene Symbol: NECTIN1
NECTIN1
0.010 Biomarker disease BEFREE <b>NEW & NOTEWORTHY</b> PRR knockdown in PVN neurons attenuates the development of DOCA-salt hypertension and autonomic dysfunction through a decrease in ERK1/2 activation in the PVN and RVLM during hypertension. 30925093 2019
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
0.010 Biomarker disease BEFREE <b>NEW & NOTEWORTHY</b> PRR knockdown in PVN neurons attenuates the development of DOCA-salt hypertension and autonomic dysfunction through a decrease in ERK1/2 activation in the PVN and RVLM during hypertension. 30925093 2019
Entrez Id: 5967
Gene Symbol: REG1A
REG1A
0.010 Biomarker disease BEFREE Subsequently, the diagnosis was changed to PSP due to hypometric downward gaze, reduced blink frequency, symmetric bradykinesia, rigidity, and the absence of autonomic dysfunction. 31216016 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.010 Biomarker disease BEFREE Patients with COPD might be particularly susceptible to hypoxia-induced autonomic dysregulation. 30936690 2019
Entrez Id: 5623
Gene Symbol: PSPN
PSPN
0.010 Biomarker disease BEFREE Subsequently, the diagnosis was changed to PSP due to hypometric downward gaze, reduced blink frequency, symmetric bradykinesia, rigidity, and the absence of autonomic dysfunction. 31216016 2019
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
0.010 AlteredExpression disease BEFREE The results suggest that parental hypertension results in elevated BP and autonomic dysfunction in adult male offspring through activation of AT1R pathway and inhibition of endogenous H<sub>2</sub>S production in the brain. 31607943 2019
Entrez Id: 10159
Gene Symbol: ATP6AP2
ATP6AP2
0.010 Biomarker disease BEFREE <b>NEW & NOTEWORTHY</b> PRR knockdown in PVN neurons attenuates the development of DOCA-salt hypertension and autonomic dysfunction through a decrease in ERK1/2 activation in the PVN and RVLM during hypertension. 30925093 2019
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
0.010 Biomarker disease BEFREE Conclusions Daytime SD of SBP is a better screening tool than nondipping status in detecting autonomic dysfunction. 30905258 2019
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.010 Biomarker disease BEFREE Conclusions Daytime SD of SBP is a better screening tool than nondipping status in detecting autonomic dysfunction. 30905258 2019
Entrez Id: 1471
Gene Symbol: CST3
CST3
0.010 Biomarker disease BEFREE Therefore, the aim of this study was to investigate the relationship between CysC and cardiovascular autonomic dysfunction in type 2 diabetic patients without renal dysfunction. 31011584 2019
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.010 Biomarker disease BEFREE We used linear mixed-effects models and reliable change indices (RCIs) to examine longitudinal associations between dysautonomia and dopamine transporter (DAT) striatal binding ratios (SBRs) measured by single-photon emission computerized tomography in PPMI participants over four years (n = 397 at baseline). 30146185 2018
Entrez Id: 3508
Gene Symbol: IGHMBP2
IGHMBP2
0.010 GeneticVariation disease BEFREE This case report confirms that IGHMBP2 related disorders can result in a severe peripheral neuropathy with gastrointestinal autonomic dysfunction requiring parenteral nutrition. 30385095 2018
Entrez Id: 2571
Gene Symbol: GAD1
GAD1
0.010 GeneticVariation disease BEFREE We report on a paediatric case of anti-GAD encephalitis with severe presentation and uncontrollable dysautonomia. 29370977 2018
Entrez Id: 79813
Gene Symbol: EHMT1
EHMT1
0.010 Biomarker disease BEFREE Increased GLP-1 in narcolepsy may suggest autonomic dysfunction with metabolic changes. 29771387 2018