Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.190 GeneticVariation disease BEFREE The results of our study show that there is no difference in dyskinesias prevalence among carriers of the two DAT gene polymorphisms. 30316985 2019
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.190 Biomarker disease BEFREE Despite a weak correlation with PD severity and progression, quantitative measurements of DAT binding at baseline could be used to predict the emergence of late-disease motor fluctuations and dyskinesias. 31405186 2019
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.190 Biomarker disease BEFREE There is a loss of the DAT in Parkinson's disease affecting release of levodopa implicated in levodopa-induced dyskinesias. 29407218 2018
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.190 Biomarker disease BEFREE The effects of levodopa sparing on dyskinesia development were assessed with Kaplan-Meier estimates and a stratified Cox regression model adjusted for age of onset, sex, dopamine transporter availability, and daily levodopa dose per weight. 30027399 2018
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.190 Biomarker disease BEFREE The DAT upregulation by rotigotine in an opposite direction with respect to early Parkinson disease compensatory mechanisms might reduce the risk of dyskinesia, but it could imply less motor benefit because of less stimulation by the dopamine itself on dopaminergic receptors. 27941527 2017
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.190 Biomarker disease BEFREE This report emphasizes the usefulness of the neopterin level in cerebrospinal fluids and dopamine transporter imaging in the differential diagnosis of DRD syndromes and a possible mechanism of levodopa-induced-dyskinesia in early childhood onset case. 24018121 2013
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.190 AlteredExpression disease BEFREE PET demonstrates reduced dopamine transporter expression in PD with dyskinesias. 19020294 2009
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.190 GeneticVariation disease BEFREE No significant difference was found in levodopa main outcome variables and dyskinesia incidence between the two groups of patients stratified by DAT VNTR polymorphism. 15190232 2004
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.190 Biomarker disease BEFREE The wealth of information about this interesting molecule that has been developed over the last 12 years has led to increased interest in DAT among workers interested in both normal and abnormal movement. 14531049 2003
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.190 Biomarker disease HPO