Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8444
Gene Symbol: DYRK3
DYRK3
0.010 Biomarker group BEFREE </p> Results:In general, nutrition is experienced, not only by athletes themselves but also by technicians and coaches, as a tool for improving performance and as such assimilated to an aspect of training but in the presence of factors of vulnerability towards the ED by of the young athletes the exaggerated tendency to manipulate the weight can determine the appearance of an eating disorder or of the so-called athletic anorexia or the RED-S. </p> Conclusions:It is important to emphasize that not only do professional athletes suffer from it, but also good-looking amateurs and amateurs. 31684854 2020
Entrez Id: 3550
Gene Symbol: IK
IK
0.010 Biomarker group BEFREE </p> Results:In general, nutrition is experienced, not only by athletes themselves but also by technicians and coaches, as a tool for improving performance and as such assimilated to an aspect of training but in the presence of factors of vulnerability towards the ED by of the young athletes the exaggerated tendency to manipulate the weight can determine the appearance of an eating disorder or of the so-called athletic anorexia or the RED-S. </p> Conclusions:It is important to emphasize that not only do professional athletes suffer from it, but also good-looking amateurs and amateurs. 31684854 2020
Entrez Id: 181
Gene Symbol: AGRP
AGRP
0.010 Biomarker group BEFREE In this chapter we will review literatures describing the functional organization of the AgRP circuit and its correlative signaling components that influence ingestive, foraging, motivational, and cognitive responses, a framework that reshaped our thinking toward the new hope and challenges in treatment of obesity and eating disorders. 30390282 2019
Entrez Id: 2899
Gene Symbol: GRIK3
GRIK3
0.010 Biomarker group BEFREE Expression analysis revealed four novel common significant genes for OCD and ED (oxytocin receptor, glutamate decarboxylase 2, neuropeptide Y and glutamate ionotropic receptor kainate type subunit 3). 30569105 2019
Entrez Id: 389203
Gene Symbol: SMIM20
SMIM20
0.010 AlteredExpression group BEFREE The PNX levels were associated with some symptoms of eating disorders which may indicate its potential contribution in the regulation of emotions and behaviors in AN. 31736434 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.010 Biomarker group BEFREE IL-2 increase was not linked to EDs, but to the interaction of depression and BMI. 31450770 2019
Entrez Id: 8239
Gene Symbol: USP9X
USP9X
0.010 Biomarker group BEFREE The aims of this study were to develop and test the Family Strengths-Oriented Therapeutic Conversation (FAM-SOTC) intervention for partner caregivers of young individuals with eating disorders (EDs). 30552746 2019
Entrez Id: 4826
Gene Symbol: NNAT
NNAT
0.010 GeneticVariation group BEFREE Our data suggest that NNAT variants and NNAT expression changes may be associated with susceptibility to eating disorders such as anorexia nervosa. 30933048 2019
Entrez Id: 80763
Gene Symbol: SPX
SPX
0.010 Biomarker group BEFREE It is hypothesized that novel neuropeptides such as phoenixin (PNX), spexin (SPX), and kisspeptin (KISS) are involved in the pathogenesis of eating disorders. 31736434 2019
Entrez Id: 4810
Gene Symbol: NHS
NHS
0.010 Biomarker group BEFREE A total of 37 predominantly heterosexual women completed a control intervention in which they read NHS leaflets on eating disorders and healthy weight. 31849745 2019
Entrez Id: 6462
Gene Symbol: SHBG
SHBG
0.010 GeneticVariation group BEFREE Forty-six women with bulimia nervosa (BN), 31 with eating disorder not otherwise specified, purging type (EDNOS P) and 56 matched healthy controls were studied with respect to serum testosterone (T), 5alpha-dihydrotestosterone (DHT), sex hormone-binding globulin (SHBG), deyhydroepiahndrosterone sulfate (DHEAS) and luteinizing hormone (LH) and to ovarian morphology. 30172682 2019
Entrez Id: 3060
Gene Symbol: HCRT
HCRT
0.010 Biomarker group BEFREE Ongoing research on the use of orexin receptor (OXR) antagonists in sleep disorders has opened a window to the pathomechanisms of NA and the potentials for OXR modulation in eating disorders and obesity. 30998932 2019
Entrez Id: 6921
Gene Symbol: ELOC
ELOC
0.010 Biomarker group BEFREE The current study evaluated the psychometric properties, including factor structure, criterion validity, and measurement invariance of the ELOC and LOCES across two groups: (a) a clinical sample of individuals with eating disorders (n = 106) and (b) a non-clinical sample of college students (n = 321). 30265751 2018
Entrez Id: 1629
Gene Symbol: DBT
DBT
0.010 Biomarker group BEFREE DBT clinicians are encouraged to implement both sets of techniques (DBT techniques and standard techniques for the treatment of eating disorders) in an integrated way. 29247895 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.010 Biomarker group BEFREE IL-1β and TGF-β did not differ between HCs and any ED group. 29906710 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.010 AlteredExpression group BEFREE TNF-α and IL-6 were elevated in ED participants compared to healthy controls (HCs). 29906710 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.010 AlteredExpression group BEFREE TNF-α and IL-6 were elevated in ED participants compared to healthy controls (HCs). 29906710 2018
Entrez Id: 4342
Gene Symbol: MOS
MOS
0.010 GeneticVariation group BEFREE Participants completed a battery of established self-report measures assessing food addiction, binge-eating and eating-disorder psychopathology (Eating Disorder Examination-Questionnaire; EDE-Q), depressive symptoms (Patient Health Questionnaire-2; PHQ-2), and mental and physical functioning (MOS Short Form Health Survey; SF-12). 29870970 2018
Entrez Id: 4922
Gene Symbol: NTS
NTS
0.010 AlteredExpression group BEFREE Previous studies have demonstrated that alterations of neurotensin levels were associated with several neuropathological conditions such as Alzheimer's disease, mood disorders, and obesity associated eating disorders. 30279001 2018
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.010 GeneticVariation group BEFREE We measured the plasma concentrations of the somatotropic hormone (GH) and the insulin-like growth factor-1 (IGF-1) in 136 patients with various forms of ED, 65 with restricted Anorexia Nervosa (ANR), 19 with bingeing-purging Anorexia Nervosa (ANBP), 12 with purging-non binging Anorexia Nervosa (ANP), 26 with Bulimia Nervosa (BN), 8 with ED not otherwise specified-anorexic type (EDNOS-AN), 7 with ED not otherwise specified-bulimic type (EDNOS-BN) and in 30 healthy controls. 29179911 2018
Entrez Id: 104355217
Gene Symbol: ERICD
ERICD
0.010 Biomarker group BEFREE Electronic databases (including the Cochrane Controlled Trial Register, MEDLINE, PsycINFO, Academic Search Complete, Global Health, CINAHL complete, Health Business Elite, Econlit, Health Policy Reference Center and ERIC) were searched for published cost-effectiveness studies of eating disorder prevention and treatment including papers published up to January 2017. 29113456 2018
Entrez Id: 2571
Gene Symbol: GAD1
GAD1
0.010 GeneticVariation group BEFREE We used the Patient Health Questionnaire-9 (PHQ-9) to screen for major depression, the Generalized Anxiety Disorder-7 (GAD-7) to screen for generalized anxiety and the SCOFF questionnaire to screen for eating disorders. 29793465 2018
Entrez Id: 2641
Gene Symbol: GCG
GCG
0.010 Biomarker group BEFREE On the basis of theoretical considerations about neurotransmitters, hormones and neural circuits, possible drug targets for the treatment of EDs may include signal molecules and receptors of the self-regulatory system such as serotonin, norepinephrine and glutamate, the hedonic system including opioids, cannabinoids and dopamine and the hypothalamic homeostatic system including histamine, ghrelin, leptin, insulin, and glucagon-like peptide-1. 28933969 2018
Entrez Id: 25859
Gene Symbol: PART1
PART1
0.010 Biomarker group BEFREE In Part 1, participants (N = 524; 54% female) completed the Eating Disorder Examination-Questionnaire and Daily Stress Inventory. 29958864 2018
Entrez Id: 72
Gene Symbol: ACTG2
ACTG2
0.010 Biomarker group BEFREE Effects of Tailored and ACT-Influenced Internet-Based CBT for Eating Disorders and the Relation Between Knowledge Acquisition and Outcome: A Randomized Controlled Trial. 28711113 2017