Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 Biomarker disease BEFREE The mechanisms may include the following pathways: [TGFB1 or TNFA]-[IL1B]-[pre-eclampsia]; [TNFA or INS]-[NOS3]-[pre-eclampsia]; [INS]-[HSPA4 or CLU]-[pre-eclampsia]; [ACE]-[MTHFR]-[pre-eclampsia]. 25879409 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 GeneticVariation disease BEFREE Maternal/newborn genotype contribution of the renin-angiotensin system (Met235Thr, Thr174Met, I/D-ACE, A2350G-ACE, A1166C-AT2R1, C3123A- AT2R2, 83A/G-REN) to the risk of pre-eclampsia: a Romanian study. 21436209 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 Biomarker disease BEFREE There were no differences in maternal or infant ACE activities in relation to onset of pre-eclampsia. 20044877 2010
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 GeneticVariation disease BEFREE The angiotensin-converting enzyme (ACE) intron 16 insertion/deletion (I/D) polymorphism is associated with ACE activity and has been discussed as a risk factor for pre-eclampsia. 19717502 2009
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 GeneticVariation disease BEFREE Synergism of angiotensin-converting enzyme I/D and other polymorphisms of renin-angiotensin system components and nitric oxide synthase may be a risk factor for pre-eclampsia. 17520398 2007
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 GeneticVariation disease BEFREE This study has found no evidence that the insertion-deletion polymorphism in the angiotensin-converting enzyme gene is associated with pre-eclampsia. 10459873 1999