Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.070 GeneticVariation disease BEFREE No statistically significant differences were observed in genotype or allele frequencies between the pre-eclampsia and normal control for the C677T polymorphism of MTHFR gene (<i>p</i> > .05). 31452430 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.070 PosttranslationalModification disease BEFREE Correlation between MTHFR gene methylation and pre-eclampsia, and its clinical significance. 26214484 2015
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.070 Biomarker disease BEFREE The mechanisms may include the following pathways: [TGFB1 or TNFA]-[IL1B]-[pre-eclampsia]; [TNFA or INS]-[NOS3]-[pre-eclampsia]; [INS]-[HSPA4 or CLU]-[pre-eclampsia]; [ACE]-[MTHFR]-[pre-eclampsia]. 25879409 2015
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.070 GeneticVariation disease BEFREE This meta-analysis suggests that the MTHFR 677T allele might be associated with increased pre-eclampsia risk in Asian and white ethnicity and the subgroup of severe pre-eclampsia, while no association is observed between the MTHFR A1298C polymorphism and pre-eclampsia. 24898880 2014
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.070 GeneticVariation disease BEFREE Methylenetetrahydrofolate reductase C677T polymorphism and Factor V Leiden variant in Mexican women with preeclampsia/eclampsia. 15905108 2005
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.070 GeneticVariation disease BEFREE Association of pre-eclampsia with hyperhomocysteinaemia and methylenetetrahydrofolate reductase gene C677T polymorphism in a Turkish population. 15387863 2004
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.070 GeneticVariation disease BEFREE We genotyped a total of 171 cases with preeclampsia or eclampsia and 185 normotensive control subjects for the methylenetetrahydrofolate reductase (MTHFR) 677 C --> T genotype. 10655155 2000