Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3320
Gene Symbol: HSP90AA1
HSP90AA1
0.030 AlteredExpression disease BEFREE The heat shock proteins hsp90 and hsp70 have been shown to be over-expressed in peripheral blood mononuclear cells from SLE patients. 1335295 1992
Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4
0.030 AlteredExpression disease BEFREE The heat shock proteins hsp90 and hsp70 have been shown to be over-expressed in peripheral blood mononuclear cells from SLE patients. 1335295 1992
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.080 Biomarker disease BEFREE To identify the factors that support it, IL-6, a cytokine with an important role in the differentiation of IgG-secreting cells, was studied in SLE patients. 2051017 1991
Entrez Id: 1378
Gene Symbol: CR1
CR1
0.020 AlteredExpression disease BEFREE Family studies were carried out to look at CR1 expression in 24 hydralazine-induced SLE patients (Hz Reactors), who had been off the drug for at least 1 year and were clinically well at the time of the study. 2958187 1987
Entrez Id: 718
Gene Symbol: C3
C3
0.040 AlteredExpression disease BEFREE On the other hand, CR1 levels of PMN stimulated by FMLP were also found to be decreased in SLE patients, while both the expression of circulating PMN (cells isolated at 4 degrees C) and the total cellular CR1 content were normal. 2974768 1988
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
0.010 AlteredExpression disease BEFREE On the other hand, CR1 levels of PMN stimulated by FMLP were also found to be decreased in SLE patients, while both the expression of circulating PMN (cells isolated at 4 degrees C) and the total cellular CR1 content were normal. 2974768 1988
Entrez Id: 1378
Gene Symbol: CR1
CR1
0.020 AlteredExpression disease BEFREE Family studies of erythrocyte complement receptor type 1 levels: reduced levels in patients with SLE are acquired, not inherited. 3987091 1985
Entrez Id: 780904
Gene Symbol: PSS
PSS
0.010 GeneticVariation disease BEFREE This compared to 4 of the 22 SLE patients (also 18%) of whom 3 had thyroid disease and one PSS. 6600509 1983
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.060 AlteredExpression disease BEFREE To determine the cellular expression and localization of interferon-gamma (IFN gamma)-inducible protein p16, a new antigen specificity of antinuclear antibodies (ANA), and to evaluate the prevalence of anti-p16, particularly in SLE patients. 7526871 1994
Entrez Id: 3320
Gene Symbol: HSP90AA1
HSP90AA1
0.030 Biomarker disease BEFREE The role of hsp90 in SLE. 7605872 1994
Entrez Id: 2335
Gene Symbol: FN1
FN1
0.010 GeneticVariation disease BEFREE These results suggest autoantibodies binding to fibronectin homology regions within the 145-kD noncollagenous domain may interfere with the adhesion function of type VII collagen and contribute to lamina densa-dermal dysadhesion in epidermolysis bullous acquisita and bullous SLE. 7684054 1993
Entrez Id: 3925
Gene Symbol: STMN1
STMN1
0.010 AlteredExpression disease BEFREE We show that the SmN gene is transcribed at significantly elevated levels in peripheral blood mononuclear cells (PBMCs) from SLE patients compared to normal controls. 7772706 1994
Entrez Id: 6638
Gene Symbol: SNRPN
SNRPN
0.010 AlteredExpression disease BEFREE We show that the SmN gene is transcribed at significantly elevated levels in peripheral blood mononuclear cells (PBMCs) from SLE patients compared to normal controls. 7772706 1994
Entrez Id: 6607
Gene Symbol: SMN2
SMN2
0.010 AlteredExpression disease BEFREE We show that the SmN gene is transcribed at significantly elevated levels in peripheral blood mononuclear cells (PBMCs) from SLE patients compared to normal controls. 7772706 1994
Entrez Id: 8926
Gene Symbol: SNURF
SNURF
0.010 AlteredExpression disease BEFREE We show that the SmN gene is transcribed at significantly elevated levels in peripheral blood mononuclear cells (PBMCs) from SLE patients compared to normal controls. 7772706 1994
Entrez Id: 6606
Gene Symbol: SMN1
SMN1
0.010 AlteredExpression disease BEFREE We show that the SmN gene is transcribed at significantly elevated levels in peripheral blood mononuclear cells (PBMCs) from SLE patients compared to normal controls. 7772706 1994
Entrez Id: 940
Gene Symbol: CD28
CD28
0.020 Biomarker disease BEFREE We found that T cells from SLE patients had significantly higher responses to CD28 than did cells from normal controls. 7888034 1994
Entrez Id: 3320
Gene Symbol: HSP90AA1
HSP90AA1
0.030 Biomarker disease BEFREE The level of the 90 kD heat shock protein (hsp90) has been shown to be elevated in the peripheral blood mononuclear cells of a subset of SLE patients. 8216691 1993
Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4
0.030 AlteredExpression disease BEFREE Elevated transcription of the hsp90 beta gene in SLE patients is not in general paralleled by enhanced transcription of the hsp70 or ubiquitin genes indicating that the hsp90 beta gene is specifically activated in some SLE patients. 8216691 1993
Entrez Id: 3326
Gene Symbol: HSP90AB1
HSP90AB1
0.010 Biomarker disease BEFREE Elevated transcription of the hsp90 beta gene in SLE patients is not in general paralleled by enhanced transcription of the hsp70 or ubiquitin genes indicating that the hsp90 beta gene is specifically activated in some SLE patients. 8216691 1993
Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4
0.030 Biomarker disease BEFREE The level of the heat inducible hsp70 protein (hsp72) has been shown to be elevated in the peripheral blood mononuclear cells of a subset of SLE patients. 8305922 1993
Entrez Id: 3303
Gene Symbol: HSPA1A
HSPA1A
0.010 Biomarker disease BEFREE The level of the heat inducible hsp70 protein (hsp72) has been shown to be elevated in the peripheral blood mononuclear cells of a subset of SLE patients. 8305922 1993
Entrez Id: 3304
Gene Symbol: HSPA1B
HSPA1B
0.010 Biomarker disease BEFREE The level of the heat inducible hsp70 protein (hsp72) has been shown to be elevated in the peripheral blood mononuclear cells of a subset of SLE patients. 8305922 1993
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
0.010 Biomarker disease BEFREE Molecular analysis of DQB1 and DQA1 alleles found in American Caucasian and American black SS (or SLE) patients demonstrated high frequencies of DQB1*0201 and DQA1*0501. 8340232 1993
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
0.010 Biomarker disease BEFREE The results show that the increase of DPB1*0101 in SLE patients is associated with the HLA-B8, DR3 haplotype and it suggests a more important role for HLA-B8, DR3 or genes within this haplotype than for DPB1*0101 in the genetic predisposition for SLE. 8399121 1993