Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | disease | BEFREE | Down-regulated NOD2 by immunosuppressants in peripheral blood cells in patients with SLE reduces the muramyl dipeptide-induced IL-10 production. | 21886831 | 2011 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression. | 24130510 | 2013 | ||||
|
0.090 | Biomarker | disease | BEFREE | We also found a significant association of serum TNF-α, interferon-α, IL-10 and IL-12 with SLE phenotypes. | 26582004 | 2016 | ||||
|
0.090 | Biomarker | disease | BEFREE | Relationship assessment and fatigue severity scale scores were found to be the best indicators of depression for the SLE patients (P = .042 and .028, respectively).Fatigue Severity, relationship satisfaction, and IL-10 concentrations are indicators of depression in lupus patients. | 29995777 | 2018 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Influence of Atg5 mutation in SLE depends on functional IL-10 genotype. | 24205307 | 2013 | ||||
|
0.090 | Biomarker | disease | BEFREE | Analysis of immunoglobulin-like transcripts (ILTs) in lymphocytes with sHLA-G and IL10 from SLE patients. | 22562117 | 2013 | ||||
|
0.090 | Biomarker | disease | BEFREE | IL10/TNFalpha interaction influences susceptibility to DLE and the appearance of specific autoantibodies in SLE patients, whereas high TNFalpha producer genotypes represent a significant risk factor for SLE. | 15800006 | 2005 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Previous studies have reported that genes relating to JAK-STAT pathway (IFIH1, TYK2 and IL-10) conferred the susceptibility to SLE. | 30171347 | 2018 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Furthermore, the IL-10 AA genotype is associated with reduced ratio of atheroprotective to atherogenic cytokines in SLE patients with CVD. | 15530917 | 2004 |