Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.090 Biomarker disease BEFREE Down-regulated NOD2 by immunosuppressants in peripheral blood cells in patients with SLE reduces the muramyl dipeptide-induced IL-10 production. 21886831 2011
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.090 Biomarker disease BEFREE We also found a significant association of serum TNF-α, interferon-α, IL-10 and IL-12 with SLE phenotypes. 26582004 2016
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.090 Biomarker disease BEFREE Relationship assessment and fatigue severity scale scores were found to be the best indicators of depression for the SLE patients (P = .042 and .028, respectively).Fatigue Severity, relationship satisfaction, and IL-10 concentrations are indicators of depression in lupus patients. 29995777 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.090 Biomarker disease BEFREE Analysis of immunoglobulin-like transcripts (ILTs) in lymphocytes with sHLA-G and IL10 from SLE patients. 22562117 2013
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.090 Biomarker disease BEFREE IL10/TNFalpha interaction influences susceptibility to DLE and the appearance of specific autoantibodies in SLE patients, whereas high TNFalpha producer genotypes represent a significant risk factor for SLE. 15800006 2005
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.090 GeneticVariation disease BEFREE Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression. 24130510 2013
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.090 GeneticVariation disease BEFREE Influence of Atg5 mutation in SLE depends on functional IL-10 genotype. 24205307 2013
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.090 GeneticVariation disease BEFREE Previous studies have reported that genes relating to JAK-STAT pathway (IFIH1, TYK2 and IL-10) conferred the susceptibility to SLE. 30171347 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.090 GeneticVariation disease BEFREE Furthermore, the IL-10 AA genotype is associated with reduced ratio of atheroprotective to atherogenic cytokines in SLE patients with CVD. 15530917 2004