Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4810
Gene Symbol: NHS
NHS
0.010 Biomarker disease BEFREE Changing trends in mortality in systemic lupus erythematosus? An analysis of SLE inpatient mortality at University Hospital Coventry and Warwickshire NHS Trust from 2007 to 2016. 31570977 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.010 AlteredExpression disease BEFREE After adjustment for multiple comparisons, GCF levels of interleukin (IL)-1β, IL-8, granulocyte colony-stimulating factor (G-CSF), interferon-γ and monocyte chemoattractant protein-1 were significantly higher, whereas the levels of granulocyte-macrophage colony-stimulating factor were significantly lower in jSLE patients. 30563424 2019
Entrez Id: 8482
Gene Symbol: SEMA7A
SEMA7A
0.010 AlteredExpression disease BEFREE No differences in plasma Sema3A and Sema7A levels were detected in SLE patients of different genotypes. 31394943 2019
Entrez Id: 688
Gene Symbol: KLF5
KLF5
0.010 AlteredExpression disease BEFREE Excessive miR-152-3p Results in Increased BAFF Expression in SLE B-Cells by Inhibiting the KLF5 Expression. 31178864 2019
Entrez Id: 9987
Gene Symbol: HNRNPDL
HNRNPDL
0.010 Biomarker disease BEFREE SLE anti-BC abs effectively compete with RNA transport factor heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) for DTE access and significantly diminish BC RNA delivery to synapto-dendritic sites of function. 31405929 2019
Entrez Id: 8639
Gene Symbol: AOC3
AOC3
0.010 Biomarker disease BEFREE This study investigated the expression of vascular adhesion protein-1 (VAP-1) in SLE patients with conjunctivitis and the relationship between VAP-1 and other proteins in the onset of the disease. 31819770 2019
Entrez Id: 55937
Gene Symbol: APOM
APOM
0.010 AlteredExpression disease BEFREE Since apoM plasma levels decrease during inflammatory conditions, our aim was also to determine the impact of SLE disease activity on apoM plasma levels. 31046824 2019
Entrez Id: 196
Gene Symbol: AHR
AHR
0.010 Biomarker disease BEFREE Association between the ratio of aryl hydrocarbon receptor (AhR) in Th17 cells to AhR in Treg cells and SLE skin lesions. 30743201 2019
Entrez Id: 1840
Gene Symbol: DTX1
DTX1
0.010 AlteredExpression disease BEFREE In addition, low DTX1 expression in SLE patients was associated with active LN, lung involvement or hypocomplementaemia. 30629240 2019
Entrez Id: 80231
Gene Symbol: CXorf21
CXorf21
0.010 Biomarker disease BEFREE Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis. 31695690 2019
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
0.010 AlteredExpression disease BEFREE SLE LDG exhibited significantly heightened surface expression of various activation markers and also of lectin-like oxidised low-density lipoprotein receptor-1, previously described to be associated with PMN-MDSC. 31040119 2019
Entrez Id: 104326055
Gene Symbol: APOA1-AS
APOA1-AS
0.010 Biomarker disease BEFREE To quantify the expression level of three lncRNAs which are known to be relevant to atherosclerosis (ANRIL, NOS3-AS, and APOA1-AS) in SLE patients and to assess their relationship with atherogenic and inflammatory biomarkers. 30128915 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.010 Biomarker disease BEFREE The aim of this study was to investigate serum S100B and brain-derived neurotrophic factor (BDNF) in systemic lupus erythematous (SLE) patients, with and without neuropsychiatric (NP) manifestation activity. 30376438 2018
Entrez Id: 6363
Gene Symbol: CCL19
CCL19
0.010 Biomarker disease BEFREE We calculated a validated composite score (IFN-CK) of three type I IFN-inducible chemokines (CCL2/CXCL10/CCL19) measured in 109 SLE patients (median 7 occasions over 3.2 years). 29459655 2018
Entrez Id: 286046
Gene Symbol: XKR6
XKR6
0.010 GeneticVariation disease BEFREE Genetic variants in systemic lupus erythematosus susceptibility loci, XKR6 and GLT1D1 are associated with childhood-onset SLE in a Korean cohort. 29967481 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.010 AlteredExpression disease BEFREE SLE disease activity and complement components may suggest regulatory effect of adipokines (adiponectin and leptin) on disease pathogenesis. 30098476 2018
Entrez Id: 1506
Gene Symbol: CTRL
CTRL
0.010 Biomarker disease BEFREE SLE and CTRL groups showed similar fasting glucose, glucose response, and skeletal muscle GLUT-4 translocation after MTT. 28320046 2018
Entrez Id: 7293
Gene Symbol: TNFRSF4
TNFRSF4
0.010 Biomarker disease BEFREE OX40L/OX40 axis impairs follicular and natural Treg function in human SLE. 30568041 2018
Entrez Id: 183
Gene Symbol: AGT
AGT
0.010 Biomarker disease BEFREE The angiotensin II receptor blocker (ARB) olmesartan has been recently associated with sprue-like enteropathy (SLE), a gastrointestinal condition characterized by intestinal malabsorption (IM) and severe diarrhea. 29457309 2018
Entrez Id: 808
Gene Symbol: CALM3
CALM3
0.010 Biomarker disease BEFREE The circulating levels of these lncRNAs were assessed using RT-PCR, in addition to measurement of E-selectin, V-CAM1, oxidized low-density lipoprotein (oxLDL), total nitric oxide (NOx), and lipid profile in 65 SLE patients (35 atherosclerotic and 30 non-atherosclerotic) and 35 healthy subjects. 30128915 2018
Entrez Id: 801
Gene Symbol: CALM1
CALM1
0.010 Biomarker disease BEFREE The circulating levels of these lncRNAs were assessed using RT-PCR, in addition to measurement of E-selectin, V-CAM1, oxidized low-density lipoprotein (oxLDL), total nitric oxide (NOx), and lipid profile in 65 SLE patients (35 atherosclerotic and 30 non-atherosclerotic) and 35 healthy subjects. 30128915 2018
Entrez Id: 10563
Gene Symbol: CXCL13
CXCL13
0.010 AlteredExpression disease BEFREE CXCL13 levels were elevated in 59% (41/70) of SLE patient visits with mild or no disease activity, but in 90% (9/10) with high disease activity. 29728857 2018
Entrez Id: 1351
Gene Symbol: COX8A
COX8A
0.010 AlteredExpression disease BEFREE Chinese SLE Treatment and Research Group (CSTAR) registry:VIII. Influence of socioeconomic and geographical variables on disease phenotype and activity in Chinese patients with SLE. 28296238 2018
Entrez Id: 144423
Gene Symbol: GLT1D1
GLT1D1
0.010 GeneticVariation disease BEFREE Genetic variants in systemic lupus erythematosus susceptibility loci, XKR6 and GLT1D1 are associated with childhood-onset SLE in a Korean cohort. 29967481 2018
Entrez Id: 567
Gene Symbol: B2M
B2M
0.010 AlteredExpression disease BEFREE SLE activity was assessed with Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K), and by measuring the levels of C3 and C4 complement components, anti-double stranded DNA antibodies (anti-dsDNA antibodies) and β2M. 29533541 2018