Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.090 Biomarker disease BEFREE IgM anti-phosphorylcholine antibodies associate with senescent and IL-17+ T cells in SLE patients with a pro-inflammatory lipid profile. 31302689 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.090 Biomarker disease BEFREE Depression in SLE patients increased the release of pro-inflammatory cytokine (IL-6 and IL-17) that in turn generating more autoantibodies and showed strong recognition to 16α-OHE<sub>1</sub>-A. 30925322 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.090 Biomarker disease BEFREE SLE NETs were decorated with tissue factor (TF) and interleukin-17A (IL-17A), which promoted thrombin generation and the fibrotic potential of cultured skin fibroblasts. 30563869 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.090 Biomarker disease BEFREE In conclusion, elevated plasma midkine and pleiotrophin levels and their associations with rash, anti-SSA and IL-17 in SLE patients suggest their involvement in this disease. 27903979 2017
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.090 AlteredExpression disease BEFREE Increased expression of TLR2 in CD4(+) T cells from SLE patients enhances immune reactivity and promotes IL-17 expression through histone modifications. 26079624 2015
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.090 AlteredExpression disease BEFREE Epistatic interaction between genetic variants in susceptibility gene ETS1 correlates with IL-17 levels in SLE patients. 23614478 2013
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.090 AlteredExpression disease BEFREE We examined relative gene expression of tumour necrosis factor-alpha (TNF-α), interferon-γ (IFN-γ) and serum levels of interleukin-17 (IL-17) and IL-23 and their association with SLEDAI (SLE disease activity index) score and organ manifestations in pSLE. 22759859 2012
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.090 Biomarker disease BEFREE Plasma IL-17A is increased in new-onset SLE patients and associated with disease activity. 20107878 2010
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.090 AlteredExpression disease BEFREE We quantified the mRNA expression of IL-17, -23, -27 and retinoic-acid-related orphan receptor (ROR)-gamma, the regulator for the development and function of TH17, in the urinary sediment of 23 subjects with active lupus nephritis, 25 subjects with a history of lupus nephritis in remission, 30 SLE patients with no history of renal involvement and 8 healthy subjects. 19773408 2009