Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
0.030 AlteredExpression group BEFREE Crosstalk between Toll-like receptor 3 and Notch signaling contributes to CD14<sup>+</sup> monocytes activity in enterovirus 71 infected hand, foot, and mouth disease. 29702280 2018
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
0.030 GeneticVariation group BEFREE The most significant association was with two T1D SNPs, rs12150079 (ZPBP2/ORMDL3/GSDMB region) (enterovirus frequency: AA 7.3%, AG 8.7%, GG 9.7%, RR = 0.86, overall p = 1.87E-02) and rs229541 (C1QTNF6/SSTR3/RAC2) (enterovirus frequency: CC 7.8%, CT 9.7%, TT 9.4%, RR = 1.13, overall p = 3.6E-02), followed by TLR8 (rs2407992) (p = 3.8E-02), TLR3 (1914926) (p = 4.9E-02), and two other T1D SNPs (IFIH1 rs3747517, p = 4.9E-02 and PTPN22, rs2476601, p = 5.3E-02). 26485223 2015
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
0.030 Biomarker group BEFREE Enterovirus 68 3C protease cleaves TRIF to attenuate antiviral responses mediated by Toll-like receptor 3. 24672048 2014