×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.800
GeneticVariation
group
UNIPROT
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.600
CausalMutation
group
CGI
×
Entrez Id:
51741
Gene Symbol:
WWOX
WWOX
0.600
CausalMutation
group
CGI
×
Entrez Id:
51741
Gene Symbol:
WWOX
WWOX
0.600
Biomarker
group
CTD_human
×
Entrez Id:
11178
Gene Symbol:
LZTS1
LZTS1
0.510
CausalMutation
group
CGI
×
Entrez Id:
1630
Gene Symbol:
DCC
DCC
0.510
CausalMutation
group
CGI
×
Entrez Id:
11178
Gene Symbol:
LZTS1
LZTS1
0.510
Biomarker
group
CTD_human
×
Entrez Id:
1630
Gene Symbol:
DCC
DCC
0.510
Biomarker
group
CTD_human
×
Entrez Id:
6049
Gene Symbol:
RNF6
RNF6
0.500
Biomarker
group
CTD_human
×
Entrez Id:
7048
Gene Symbol:
TGFBR2
TGFBR2
0.500
CausalMutation
group
CGI
×
Entrez Id:
6049
Gene Symbol:
RNF6
RNF6
0.500
CausalMutation
group
CGI
×
Entrez Id:
6657
Gene Symbol:
SOX2
SOX2
0.330
GenomicAlterations
group
CGI
×
Entrez Id:
6794
Gene Symbol:
STK11
STK11
0.150
Biomarker
group
HPO
×
Entrez Id:
79651
Gene Symbol:
RHBDF2
RHBDF2
0.140
Biomarker
group
HPO
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
0.100
Biomarker
group
HPO
×
Entrez Id:
6391
Gene Symbol:
SDHC
SDHC
0.100
Biomarker
group
HPO
×
Entrez Id:
6389
Gene Symbol:
SDHA
SDHA
0.100
Biomarker
group
HPO
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.100
Biomarker
group
HPO
×
Entrez Id:
5156
Gene Symbol:
PDGFRA
PDGFRA
0.100
Biomarker
group
HPO
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.600
AlteredExpression
group
BEFREE
Thus, changes in gene copy number or level of expression of HER-I or c-myc DNA sequences may play an important role in the pathogenesis of esophageal cancer in this high-risk region.
2459070
1988
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.600
GeneticVariation
group
BEFREE
Frequent mutation of the p53 gene in human esophageal cancer .
2263646
1990
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.600
Biomarker
group
BEFREE
Genetic analysis of human esophageal tumors from two high incidence geographic areas: frequent p53 base substitutions and absence of ras mutations.
1855226
1991
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.600
PosttranslationalModification
group
BEFREE
The identification of allelic loss in approximately half of the tumors analyzed supports the hypothesis that inactivation of p53 is involved in the pathogenesis of esophageal cancer .
2052580
1991
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.600
Biomarker
group
BEFREE
However, the finding of p53 mutations in Barrett's epithelium adjacent to adenocarcinomas may have clinical implications for p53 as a premalignant marker for esophageal cancer .
1943188
1991
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.600
GeneticVariation
group
BEFREE
Archival analysis of p53 genetic and protein alterations in Chinese esophageal cancer .
1923503
1991