Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55120
Gene Symbol: FANCL
FANCL
0.700 CausalMutation disease CLINVAR
Entrez Id: 84464
Gene Symbol: SLX4
SLX4
0.700 GeneticVariation disease CLINVAR
Entrez Id: 55120
Gene Symbol: FANCL
FANCL
0.700 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 2188
Gene Symbol: FANCF
FANCF
0.500 CausalMutation disease CLINVAR
Entrez Id: 55215
Gene Symbol: FANCI
FANCI
0.500 GeneticVariation disease CLINVAR
Entrez Id: 2187
Gene Symbol: FANCB
FANCB
0.480 GeneticVariation disease CLINVAR
Entrez Id: 7398
Gene Symbol: USP1
USP1
0.260 Biomarker disease MGD
Entrez Id: 2620
Gene Symbol: GAS2
GAS2
0.100 CausalMutation disease CLINVAR
Entrez Id: 5428
Gene Symbol: POLG
POLG
0.100 GeneticVariation disease CLINVAR
Entrez Id: 5428
Gene Symbol: POLG
POLG
0.100 CausalMutation disease CLINVAR
Entrez Id: 7150
Gene Symbol: TOP1
TOP1
0.010 Biomarker disease BEFREE Further studies on compartmentalisation of DNA-topoisomerase I in Fanconi anemia tissue. 6096255 1984
Entrez Id: 94233
Gene Symbol: OPN4
OPN4
0.020 Biomarker disease BEFREE In contrast treatment with higher (but not saturating) doses of 8-MOP plus UVA allowed us to distinguish two classes among the FA cell lines. 4018790 1985
Entrez Id: 57486
Gene Symbol: NLN
NLN
0.020 Biomarker disease BEFREE In contrast treatment with higher (but not saturating) doses of 8-MOP plus UVA allowed us to distinguish two classes among the FA cell lines. 4018790 1985
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
0.020 Biomarker disease BEFREE In contrast treatment with higher (but not saturating) doses of 8-MOP plus UVA allowed us to distinguish two classes among the FA cell lines. 4018790 1985
Entrez Id: 57486
Gene Symbol: NLN
NLN
0.020 Biomarker disease BEFREE Since FA cells were almost equally sensitive to 8-MOP and PyPs photoaddition and demonstrated a higher sensitivity to SCE induction by 8-MOP than normal cells, it can be concluded that this latter difference is mainly due to cross-links. 3755219 1986
Entrez Id: 94233
Gene Symbol: OPN4
OPN4
0.020 Biomarker disease BEFREE Since FA cells were almost equally sensitive to 8-MOP and PyPs photoaddition and demonstrated a higher sensitivity to SCE induction by 8-MOP than normal cells, it can be concluded that this latter difference is mainly due to cross-links. 3755219 1986
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
0.020 Biomarker disease BEFREE Since FA cells were almost equally sensitive to 8-MOP and PyPs photoaddition and demonstrated a higher sensitivity to SCE induction by 8-MOP than normal cells, it can be concluded that this latter difference is mainly due to cross-links. 3755219 1986
Entrez Id: 847
Gene Symbol: CAT
CAT
0.010 Biomarker disease BEFREE However, Mn-SOD, catalase, and glutathione peroxidase activities were consistently higher in FA fibroblasts. 3623559 1987
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.090 Biomarker disease BEFREE The expression of lymphocyte surface markers as well as the production of interleukin-2 (IL-2) and interferon-gamma (IFN) by mitogen-stimulated peripheral blood mononuclear cells (MNC) have been studied in five children with constitutional aplastic anemia. 2484652 1988
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
0.030 Biomarker disease BEFREE The expression of lymphocyte surface markers as well as the production of interleukin-2 (IL-2) and interferon-gamma (IFN) by mitogen-stimulated peripheral blood mononuclear cells (MNC) have been studied in five children with constitutional aplastic anemia. 2484652 1988
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
0.030 Biomarker disease BEFREE The expression of lymphocyte surface markers as well as the production of interleukin-2 (IL-2) and interferon-gamma (IFN) by mitogen-stimulated peripheral blood mononuclear cells (MNC) have been studied in five children with constitutional aplastic anemia. 2484652 1988
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.020 Biomarker disease BEFREE The expression of lymphocyte surface markers as well as the production of interleukin-2 (IL-2) and interferon-gamma (IFN) by mitogen-stimulated peripheral blood mononuclear cells (MNC) have been studied in five children with constitutional aplastic anemia. 2484652 1988
Entrez Id: 1719
Gene Symbol: DHFR
DHFR
0.010 GeneticVariation disease BEFREE 8MOP+UVA-induced cross-links in the dhfr gene were completely repaired by 12 h in one normal and one Fanconi's anaemia (FA) group A cell line. 2544311 1989
Entrez Id: 3251
Gene Symbol: HPRT1
HPRT1
0.040 GeneticVariation disease BEFREE Hypomutability in Fanconi anemia cells is associated with increased deletion frequency at the HPRT locus. 2236046 1990
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.020 AlteredExpression disease BEFREE Although LCLs tended to exhibit a higher SOD level than fibroblasts due to an elevation of Cu/Zn-SOD activity, BS and FA fibroblasts with increased frequencies of CAs and/or SCEs showed abnormally elevated SOD activity due to the manifold increase of Mn-SOD levels compared with control cells. 2366819 1990