Gene: NR1H3 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.350 AlteredExpression disease BEFREE Our results demonstrate that LQ has an efficacy to activate Nrf2, which contributes to inhibiting the activity of LXRα that leads to SREBP-1c induction and hepatic steatosis. 20677908 2011
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.350 Biomarker disease BEFREE Inhibition of liver X receptor-α-dependent hepatic steatosis by isoliquiritigenin, a licorice antioxidant flavonoid, as mediated by JNK1 inhibition. 20840863 2010
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.350 Biomarker disease BEFREE A deficiency of Nrf2 enhanced the ability of LXRα agonist to promote hepatic steatosis, as mediated by lipogenic gene induction. 21504366 2011
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.350 Biomarker disease BEFREE Liver X receptor α-mediated regulation of lipogenesis by core and NS5A proteins contributes to HCV-induced liver steatosis and HCV replication. 22641099 2012
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.350 Biomarker disease CTD_human Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction. 23651738 2013
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.350 GeneticVariation disease BEFREE In conclusion, PRMT3 translocation by PA is coupled to the binding of LXRα, which is responsible for the onset of fatty liver. 25187371 2015