Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3
0.350 GeneticVariation disease BEFREE In conclusion, PRMT3 translocation by PA is coupled to the binding of LXRα, which is responsible for the onset of fatty liver. 25187371 2015
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3
0.350 Biomarker disease CTD_human Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction. 23651738 2013
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3
0.350 Biomarker disease BEFREE Liver X receptor α-mediated regulation of lipogenesis by core and NS5A proteins contributes to HCV-induced liver steatosis and HCV replication. 22641099 2012
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3
0.350 AlteredExpression disease BEFREE Our results demonstrate that LQ has an efficacy to activate Nrf2, which contributes to inhibiting the activity of LXRα that leads to SREBP-1c induction and hepatic steatosis. 20677908 2011
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3
0.350 Biomarker disease BEFREE A deficiency of Nrf2 enhanced the ability of LXRα agonist to promote hepatic steatosis, as mediated by lipogenic gene induction. 21504366 2011
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3
0.350 Biomarker disease BEFREE Inhibition of liver X receptor-α-dependent hepatic steatosis by isoliquiritigenin, a licorice antioxidant flavonoid, as mediated by JNK1 inhibition. 20840863 2010