Gene: PPARD ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5467
Gene Symbol: PPARD
PPARD 		0.360 Biomarker disease BEFREE PPARδ attenuates hepatic steatosis through autophagy-mediated fatty acid oxidation. 30814493 2019
Entrez Id: 5467
Gene Symbol: PPARD
PPARD 		0.360 AlteredExpression disease BEFREE The mRNA level of Pparγ was also upregulated while Pparδ gene expression was significantly reduced during the development of hepatic steatosis. 30120929 2018
Entrez Id: 5467
Gene Symbol: PPARD
PPARD 		0.360 Biomarker disease CTD_human PPARβ/δ modulates ethanol-induced hepatic effects by decreasing pyridoxal kinase activity. 23851158 2013
Entrez Id: 5467
Gene Symbol: PPARD
PPARD 		0.360 AlteredExpression disease BEFREE In conclusion, OA activates GPR40-PLC-calcium pathway to increase the expression of PPARδ and PPARδ further decreased the expression of PTEN to regulate insulin sensitivity in hepatic steatosis. 22209682 2012
Entrez Id: 5467
Gene Symbol: PPARD
PPARD 		0.360 Biomarker disease BEFREE We investigated the effects of PPAR-δ agonist GW0742 on fatty liver changes in OLETF rats. 22824914 2012
Entrez Id: 5467
Gene Symbol: PPARD
PPARD 		0.360 AlteredExpression disease BEFREE Pharmacological activation of peroxisome proliferator-activated receptor δ improves insulin resistance and hepatic steatosis in high fat diet-induced diabetic mice. 21725906 2011
Entrez Id: 5467
Gene Symbol: PPARD
PPARD 		0.360 AlteredExpression disease BEFREE Furthermore, overexpression of PPARdelta by intravenous infection with the PPARdelta adenovirus induced the expression of Insig-1, suppressed SREBP-1 activation, and, consequently, ameliorated hepatic steatosis in obese db/db mice. 18627005 2008