Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2120
Gene Symbol: ETV6
ETV6
0.330 FusionGene disease ORPHANET
Entrez Id: 4916
Gene Symbol: NTRK3
NTRK3
0.320 FusionGene disease ORPHANET
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
0.130 Biomarker disease HPO
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
0.120 Biomarker disease HPO
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
0.110 Biomarker disease HPO
Entrez Id: 2303
Gene Symbol: FOXC2
FOXC2
0.100 Biomarker disease HPO
Entrez Id: 6772
Gene Symbol: STAT1
STAT1
0.030 AlteredExpression disease BEFREE 276, 44365-44368) that IFN-beta induction of beta-R1 in fibrosarcoma cells required transcription factors ISGF-3 and NF-kappa B. IFN-beta treatment did not augment the abundance of NF-kappa B, but led to phosphorylation of the NF-kappa B subunit p65 and induced a nuclear activity capable of phosphorylating a p65-GST fusion construct in the carboxy-terminal transactivation domain (TAD), residues 354-551. 12169689 2002
Entrez Id: 6773
Gene Symbol: STAT2
STAT2
0.010 AlteredExpression disease BEFREE 276, 44365-44368) that IFN-beta induction of beta-R1 in fibrosarcoma cells required transcription factors ISGF-3 and NF-kappa B. IFN-beta treatment did not augment the abundance of NF-kappa B, but led to phosphorylation of the NF-kappa B subunit p65 and induced a nuclear activity capable of phosphorylating a p65-GST fusion construct in the carboxy-terminal transactivation domain (TAD), residues 354-551. 12169689 2002
Entrez Id: 10379
Gene Symbol: IRF9
IRF9
0.010 AlteredExpression disease BEFREE 276, 44365-44368) that IFN-beta induction of beta-R1 in fibrosarcoma cells required transcription factors ISGF-3 and NF-kappa B. IFN-beta treatment did not augment the abundance of NF-kappa B, but led to phosphorylation of the NF-kappa B subunit p65 and induced a nuclear activity capable of phosphorylating a p65-GST fusion construct in the carboxy-terminal transactivation domain (TAD), residues 354-551. 12169689 2002
Entrez Id: 2120
Gene Symbol: ETV6
ETV6
0.330 GeneticVariation disease BEFREE ETV6 rearrangements in patients with infantile fibrosarcomas and congenital mesoblastic nephromas by fluorescence in situ hybridization. 11743047 2001
Entrez Id: 27236
Gene Symbol: ARFIP1
ARFIP1
0.010 Biomarker disease LHGDN Arfaptin 1 inhibits ADP-ribosylation factor-dependent matrix metalloproteinase-9 secretion induced by phorbol ester in HT 1080 fibrosarcoma cells. 12606037 2003
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.100 Biomarker disease BEFREE Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties. 1400481 1992
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 Biomarker disease BEFREE TNF biological activity was tested against the TNF-susceptible fibrosarcoma WEHI 164 clone 13.(ABSTRACT TRUNCATED AT 250 WORDS) 1450672 1992
Entrez Id: 84654
Gene Symbol: SPZ1
SPZ1
0.010 Biomarker disease BEFREE Spz1-transfected cells formed colony foci on soft agar and developed fibrosarcoma tumors in nude mice. 15899793 2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.040 AlteredExpression disease BEFREE Transforming growth factor-beta1 induces tissue inhibitor of metalloproteinase-1 expression via activation of extracellular signal-regulated kinase and Sp1 in human fibrosarcoma cells. 16547158 2006
Entrez Id: 9590
Gene Symbol: AKAP12
AKAP12
0.010 Biomarker disease BEFREE AKAP12 induces apoptotic cell death in human fibrosarcoma cells by regulating CDKI-cyclin D1 and caspase-3 activity. 17442483 2007
Entrez Id: 2821
Gene Symbol: GPI
GPI
0.050 AlteredExpression disease BEFREE PGI/AMF cellular expression in HT1080 human fibrosarcoma was down-regulated by small interfering RNA methodology, which resulted in an increased sensitivity to oxidative stress and oxidative stress-induced cellular senescence. 17925402 2007
Entrez Id: 633
Gene Symbol: BGN
BGN
0.010 AlteredExpression disease BEFREE PGI/AMF cellular expression in HT1080 human fibrosarcoma was down-regulated by small interfering RNA methodology, which resulted in an increased sensitivity to oxidative stress and oxidative stress-induced cellular senescence. 17925402 2007
Entrez Id: 54858
Gene Symbol: PGPEP1
PGPEP1
0.010 AlteredExpression disease BEFREE PGI/AMF cellular expression in HT1080 human fibrosarcoma was down-regulated by small interfering RNA methodology, which resulted in an increased sensitivity to oxidative stress and oxidative stress-induced cellular senescence. 17925402 2007
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.070 AlteredExpression disease BEFREE HIF-1 inhibition by chetomin effectively reduces hypoxia-dependent transcription and radiosensitizes hypoxic HT 1080 human fibrosarcoma cells in vitro. 17999771 2007
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
0.020 AlteredExpression disease BEFREE HIF-1 inhibition by chetomin effectively reduces hypoxia-dependent transcription and radiosensitizes hypoxic HT 1080 human fibrosarcoma cells in vitro. 17999771 2007
Entrez Id: 7349
Gene Symbol: UCN
UCN
0.010 AlteredExpression disease BEFREE UCN-01 also exhibited significant antitumor activity against two murine tumor models (fibrosarcoma, K-BALB and M-MSV-BALB), which activated the v-ras and v-mos oncogenes, showing a minimum treated/control ratio of 0.27 (P less than 0.01) and 0.21 (P less than 0.01). 1893379 1991
Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
0.010 Biomarker disease BEFREE FMS-1 cells showed a fibrosarcoma-like or epithelioid pattern in the heterotransplanted tumor, compared with a fascicular growth pattern of short-spindle tumor cells in the primary tumor. 19921253 2009
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.070 AlteredExpression disease BEFREE HIF-1α expression in HT 1080 human fibrosarcoma cells in vitro was silenced using HIF-1α siRNA sequence primers. 21437769 2011
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
0.010 AlteredExpression disease BEFREE Filamin A controls matrix metalloproteinase activity and regulates cell invasion in human fibrosarcoma cells. 22595522 2012