Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5376
Gene Symbol: PMP22
PMP22
0.010 Biomarker group BEFREE <b>Methods:</b> Two established models of experimental colitis, namely chemically-induced DSS colitis and the spontaneous colitis that develops in <i>Muc2</i> deficient mice, were used to assess whether QBECO treatment could ameliorate gastrointestinal disease. 30319652 2018
Entrez Id: 190
Gene Symbol: NR0B1
NR0B1
0.010 Biomarker group BEFREE <b>Methods:</b> Two established models of experimental colitis, namely chemically-induced DSS colitis and the spontaneous colitis that develops in <i>Muc2</i> deficient mice, were used to assess whether QBECO treatment could ameliorate gastrointestinal disease. 30319652 2018
Entrez Id: 4359
Gene Symbol: MPZ
MPZ
0.010 Biomarker group BEFREE <b>Methods:</b> Two established models of experimental colitis, namely chemically-induced DSS colitis and the spontaneous colitis that develops in <i>Muc2</i> deficient mice, were used to assess whether QBECO treatment could ameliorate gastrointestinal disease. 30319652 2018
Entrez Id: 6343
Gene Symbol: SCT
SCT
0.010 Biomarker group BEFREE Secretin-stimulated pancreatic/duodenal juice from 15 individuals undergoing endoscopic investigation for upper gastrointestinal disease was also analyzed. 15701843 2005
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.020 AlteredExpression group BEFREE MDR1 expression is strongly decreased in inflamed IE of patients with gastrointestinal disorders and this is independent of PXR protein levels. 17262809 2007
Entrez Id: 23158
Gene Symbol: TBC1D9
TBC1D9
0.010 AlteredExpression group BEFREE MDR1 expression is strongly decreased in inflamed IE of patients with gastrointestinal disorders and this is independent of PXR protein levels. 17262809 2007
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
0.020 Biomarker group BEFREE Eotaxin-1 has been implicated in gastrointestinal disorders and may play an important role in colorectal mucosal immunity. 17672898 2007
Entrez Id: 4069
Gene Symbol: LYZ
LYZ
0.010 AlteredExpression group BEFREE Lysozyme is an enzyme found in biological fluids, which is upregulated in leukemia, renal diseases as well as in a number of inflammatory gastrointestinal diseases. 27037159 2017
Entrez Id: 5122
Gene Symbol: PCSK1
PCSK1
0.010 GeneticVariation group BEFREE PCSK1 Mutations and Human Endocrinopathies: From Obesity to Gastrointestinal Disorders. 27187081 2016
Entrez Id: 2150
Gene Symbol: F2RL1
F2RL1
0.010 Biomarker group BEFREE Protease activated receptor 2 (PAR2) is associated with metabolism, obesity, inflammatory, respiratory and gastrointestinal disorders, pain, cancer, and other diseases. 28169521 2017
Entrez Id: 1302
Gene Symbol: COL11A2
COL11A2
0.010 Biomarker group BEFREE PARP inhibition has been proposed as a valuable strategy for treating these gastrointestinal disorders. 28302009 2017
Entrez Id: 142
Gene Symbol: PARP1
PARP1
0.010 Biomarker group BEFREE PARP inhibition has been proposed as a valuable strategy for treating these gastrointestinal disorders. 28302009 2017
Entrez Id: 4883
Gene Symbol: NPR3
NPR3
0.030 Biomarker group BEFREE Guanylate cyclase-C as a therapeutic target in gastrointestinal disorders. 29563144 2018
Entrez Id: 57511
Gene Symbol: COG6
COG6
0.010 Biomarker group BEFREE COG6-CDG is a rare autosomal recessive disease of congenital disorders of glycosylation (CDG) caused by deficiency of subunit 6 of the conserved oligomeric Golgi complex (COG6), which is characterized by growth retardation, developmental disability, microcephaly, liver and gastrointestinal disease, recurrent infections and hypohidrosis/hyperthermia. 29709711 2019
Entrez Id: 50616
Gene Symbol: IL22
IL22
0.010 Biomarker group BEFREE IL-22 is the most intensively studied cytokine within this family in contexts of gastrointestinal disease, but the importance of other family members is more and more appreciated. 29967613 2018
Entrez Id: 4883
Gene Symbol: NPR3
NPR3
0.030 Biomarker group BEFREE Guanylate cyclase-C (GC-C) is a multifunctional receptor encoded by the <i>GUCY2C</i> gene, representing an attractive target for therapy in several gastrointestinal diseases in humans. 31611814 2019
Entrez Id: 5047
Gene Symbol: PAEP
PAEP
0.010 Biomarker group BEFREE A combination therapy of pegylated interferon alfa-2a and ribavirin (PEG-IFNa/RBV) is a standard treatment, but the effect of this antiviral therapy needs evaluation as to determine the efficacy and safety of dual PEG-IFNa/RBV therapy in treating patients infected with HCV in Myanmar.This was a retrospective analysis of data from a single clinic exclusively for gastrointestinal diseases in Yangon, Myanmar. 26222859 2015
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
0.100 GeneticVariation group GWASCAT A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus. 24121790 2013
Entrez Id: 23373
Gene Symbol: CRTC1
CRTC1
0.100 GeneticVariation group GWASCAT A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus. 24121790 2013
Entrez Id: 56033
Gene Symbol: BARX1
BARX1
0.100 GeneticVariation group GWASCAT A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus. 24121790 2013
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.010 Biomarker group BEFREE According to our data, RDW was found to be a valuable prognostic index in gastrointestinal disorders along with additional inflammatory biomarkers (<i>i.e</i>., C reactive protein, erythrocyte sedimentation rate, and platelet count) and current disease severity indices used in clinical practice. 28785142 2017
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
0.010 Biomarker group BEFREE According to this survey, only a minor portion of the 44 medicinal plants considered in EMA monographs for the treatment of gastrointestinal diseases has been studied so far with regard to potential interactions with gut microbiota. 31408679 2019
Entrez Id: 2108
Gene Symbol: ETFA
ETFA
0.010 Biomarker group BEFREE According to this survey, only a minor portion of the 44 medicinal plants considered in EMA monographs for the treatment of gastrointestinal diseases has been studied so far with regard to potential interactions with gut microbiota. 31408679 2019
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.300 Biomarker group CTD_human ACTH therapy in infantile spasms: side effects. 6254450 1980
Entrez Id: 4638
Gene Symbol: MYLK
MYLK
0.300 Biomarker group CTD_human Acute stress-induced hypersensitivity to colonic distension depends upon increase in paracellular permeability: role of myosin light chain kinase. 15621374 2005