Gene: MYOC ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Septuagenarian's phenotype leads to ascertainment of familial MYOC gene mutation. 12671462 2003
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Penetrance and phenotype of the Cys433Arg myocilin mutation in a family pedigree with primary open-angle glaucoma. 12671463 2003
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 Biomarker disease BEFREE Myocilin is a gene linked to open-angle glaucomas. 12847420 2003
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease BEFREE Mutations in the myocilin gene in families with primary open-angle glaucoma and juvenile open-angle glaucoma. 12860809 2003
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Mutations in the myocilin gene in families with primary open-angle glaucoma and juvenile open-angle glaucoma. 12860809 2003
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Mutational analysis of the Myocilin gene in patients with primary open-angle glaucoma in Morocco. 12868033 2003
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Myocilin analysis by DHPLC in French POAG patients: increased prevalence of Q368X mutation. 12872267 2003
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Glaucoma phenotype in pedigrees with the myocilin Thr377Met mutation. 12912696 2003
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells. 14680806 2003
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN [Single nucleotide polymorphisms of the myocilin gene in primary open-angle glaucoma patients]. 14767915 2004
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease BEFREE However, reports on MYOC mutations in Indian primary open-angle glaucoma (POAG) patients and juvenile open-angle glaucoma (JOAG) patients are sparse. 15025728 2004
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Genetic analysis of an Indian family with members affected with juvenile-onset primary open-angle glaucoma. 15255110 2004
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Polymorphisms in the myocilin promoter unrelated to the risk and severity of primary open-angle glaucoma. 15354075 2004
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease BEFREE Formation of heteromeric WT/mutant complexes may provide a critical mechanism by which mutant myocilin polypeptides produce autosomal dominant open-angle glaucoma. 15452063 2004
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Mutations including the promoter region of myocilin/TIGR gene. 15483649 2005
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Novel MYOC gene mutation, Phe369Leu, in Japanese patients with primary open-angle glaucoma detected by denaturing high-performance liquid chromatography. 15534471 2004
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 Biomarker disease BEFREE To study the role of myocilin (MYOC) as a susceptibility gene for juvenile- and adult-onset open-angle glaucoma (JOAG and POAG, respectively). 15823921 2005
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Confirmation of the adult-onset primary open angle glaucoma locus GLC1B at 2cen-q13 in an Australian family. 16374045 2006
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease BEFREE Novel myocilin mutation in a Chinese family with juvenile-onset open-angle glaucoma. 16401791 2006
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Novel myocilin mutation in a Chinese family with juvenile-onset open-angle glaucoma. 16401791 2006
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN A large GLC1C Greek family with a myocilin T377M mutation: inheritance and phenotypic variability. 16431959 2006
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 Biomarker disease BEFREE To evaluate the noelin 2 gene as a disease-causing factor for open-angle glaucoma (OAG) and the interactions between the noelin 2 (OLFM2), optineurin (OPTN), and myocilin (MYOC) genes. 17122126 2006
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease BEFREE Patients with a myocilin mutation had glaucoma diagnosed earlier (P < 0.001) and had higher maximum recorded intraocular pressures (P < 0.001) than did the control OAG subjects. 17197538 2007
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease BEFREE Myocilin variants in Indian patients with open-angle glaucoma. 17562996 2007
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		0.700 GeneticVariation disease LHGDN Role of CYP1B1, MYOC, OPTN, and OPTC genes in adult-onset primary open-angle glaucoma: predominance of CYP1B1 mutations in Indian patients. 17563717 2007