Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1316
Gene Symbol: KLF6
KLF6 		0.350 CausalMutation disease CGI
Entrez Id: 23152
Gene Symbol: CIC
CIC 		0.330 CausalMutation disease CGI
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1 		0.320 CausalMutation disease CGI
Entrez Id: 1031
Gene Symbol: CDKN2C
CDKN2C 		0.320 GenomicAlterations disease CGI
Entrez Id: 1031
Gene Symbol: CDKN2C
CDKN2C 		0.320 CausalMutation disease CGI
Entrez Id: 324
Gene Symbol: APC
APC 		0.320 GenomicAlterations disease CGI
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.320 GeneticVariation disease UNIPROT
Entrez Id: 238
Gene Symbol: ALK
ALK 		0.320 CausalMutation disease CGI
Entrez Id: 324
Gene Symbol: APC
APC 		0.320 CausalMutation disease CGI
Entrez Id: 8880
Gene Symbol: FUBP1
FUBP1 		0.320 CausalMutation disease CGI
Entrez Id: 545
Gene Symbol: ATR
ATR 		0.310 CausalMutation disease CGI
Entrez Id: 1755
Gene Symbol: DMBT1
DMBT1 		0.310 GeneticVariation disease UNIPROT
Entrez Id: 5395
Gene Symbol: PMS2
PMS2 		0.310 CausalMutation disease CGI
Entrez Id: 10735
Gene Symbol: STAG2
STAG2 		0.300 CausalMutation disease CGI
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.300 Biomarker disease CTD_human
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.120 Biomarker disease HPO
Entrez Id: 2737
Gene Symbol: GLI3
GLI3 		0.110 Biomarker disease HPO
Entrez Id: 4041
Gene Symbol: LRP5
LRP5 		0.100 Biomarker disease HPO
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		0.100 Biomarker disease BEFREE <b>Abbreviations</b>: CryoTEM: cryo-transmission electron microscopy; DIFF: differentiated GSCs; EGF: epidermal growth factor; DUC: differential ultracentrifugation; EV: extracellular vesicle; FGF: fibroblast growth factor; GBM: glioblastoma multiforme; GFAP: glial fibrillary acidic protein; GO: gene ontology; GSC: glioma stem cells; HBEC-5i: human brain endothelial cells; MES: mesenchymal cells; MTS - [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; PMT1: proneural-to-mesenchyman transition cell line 1; PN: proneural cells; TEM: transmission electron microscopy; WB: western blotting. 30034643 2018
Entrez Id: 7045
Gene Symbol: TGFBI
TGFBI 		0.030 Biomarker disease BEFREE <b>Background:</b> Transforming growth factor-beta-induced (TGFBI) is an exocrine protein, which has been found to be able to promote the development of nasopharyngeal carcinoma, glioma, pancreatic cancer, and other tumors. 31440088 2019
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.250 AlteredExpression disease BEFREE <b>Conclusion:</b> Overexpression of HMGB1 is not associated with the malignancy and outcome in glioma. 31241346 2019
Entrez Id: 4325
Gene Symbol: MMP16
MMP16 		0.010 Biomarker disease BEFREE <b>Conclusion:</b> Sev impeded cell migration and invasion through regulating miR-146b-5p and MMP16 in glioma, indicating a novel theories foundation for the application of anesthetics like Sev in glioma. 31385537 2019
Entrez Id: 2321
Gene Symbol: FLT1
FLT1 		0.080 Biomarker disease BEFREE <b>Conclusion:</b> SUV quantification of <sup>18</sup>F-FLT uptake in glioma had an RC in the range of 18%-24% when imaging began 1 h after <sup>18</sup>F-FLT administration. 27688473 2017
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		0.100 AlteredExpression disease BEFREE <b>Conclusion:</b> The effects of CAPON-L overexpression on glioma cell proliferation are dependent on the AKT/mTOR/P53 activity. 31171914 2019
Entrez Id: 4194
Gene Symbol: MDM4
MDM4 		0.200 AlteredExpression disease BEFREE <b>Conclusion:</b> The synergistic effects, such as a higher inhibition rate, and lower expressions of MRP1 and VEGF, of combined curcumin and LFLIU against glioma was much better than that of a single treatment. 31190861 2019