Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE The aim of this study was to develop HER2-targeted peptide for glioma tumor imaging.<b>Material and methods:</b> HYNIC-(Ser)<sub>3</sub>-LTVPWY peptide was labeled with technetium-99m in presence of EDDA/tricine mixture as co-ligands. 31829777 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE The pipeline was applied to glioma scRNA-seq data and revealed a tumor-associated microglia/macrophage-mediated EGFR/ERBB2 feedback-crosstalk signaling module, which was defined as a multilayer network biomarker (MNB) to predict survival outcome and therapeutic response of glioma patients. 31329830 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE In this study, we reveal a gender difference in the prognostic value of concomitant AIB1 and HER2 CNG in glioma patients which were barely noticed before. 30153912 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE High serum ErbB2 concentration was also associated with glioma risk overall (P = 0.049; OR = 1.39, 95 % CI = 1.00-1.93). 26906551 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 GeneticVariation disease BEFREE Immunotherapy with genetically modified T cells expressing chimeric antigen receptors (CARs) targeting interleukin (IL) 13Rα2, human epidermal growth factor receptor 2, epidermal growth factor variant III or erythropoietin-producing hepatocellular carcinoma A2 has shown promise for the treatment of glioma in preclinical models. 24841514 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 AlteredExpression disease BEFREE ERBB2 expression is closely related to the invasiveness of glioma TJ905 cells. 24144028 2013
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 GeneticVariation disease BEFREE C-erbB-2 protooncogene alteration is an early phenomenon in glial tumor development and progression. 21804458 2011
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 GeneticVariation disease BEFREE We investigated the genetic variants of EGFR, ERBB2, VEGFR and their ligands, EGF and VEGF on glioma and glioblastoma risk. 20446891 2010
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE For example, Temozolomide (TMZ) exhibits some antitumor activity against brain tumors, so does Trastuzumab (Herceptin, Her-2 inhibitor), which might be effective against Her2 neu overexpressing gliomas. 19738431 2009
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE Beforehand we showed that potassium channel agonists when intracarotidly administered increased carboplatin and Her-2 antibody delivery in animal glioma models by triggering formation of brain vascular endothelial transcytotic vesicles. 19027730 2009
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease LHGDN We show here that glioma BK channels are a downstream target of erbB2/neuregulin signaling. 15948146 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 AlteredExpression disease LHGDN DNA topoisomerase IIalpha and Her-2/neu gene dosages in pediatric malignant gliomas. 15809708 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE Epidermal growth factor receptor family (EGFR, ErbB2-4) in gliomas and meningiomas. 15148612 2004
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 AlteredExpression disease BEFREE In this series the overexpression of neu/c-erbB-2 parallels glioma progression. 7914508 1994
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease CTD_human