Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 AlteredExpression disease BEFREE Furthermore, inhibition of FBXW7 and DKK3 expression suppressed the miR-25-induced effects on glioma cell proliferation and migration. 31258712 2019
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 AlteredExpression disease BEFREE Taken together, we firstly demonstrated the tumor suppressive lncRNA, Linc00320, is down-regulated in Glioma tissues and inhibits Glioma cell proliferation by restraining Wnt/β-catenin signaling through segregating β-catenin and TCF4 and revealed the novel HMGB1/Linc00320/β-catenin axis in Glioma progression. 30503496 2019
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 AlteredExpression disease BEFREE Here, we report that miR-517a expression was up-regulated in glioma tissues when compared with normal brain tissues, and up-regulation of miR-517a level is tightly correlated with the status of pathology classification of glioma. 30962271 2019
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 Biomarker disease BEFREE UPF1 is down-regulated in glioma and alleviates the progression of glioma via targeting CYTOR. 31799670 2019
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 AlteredExpression disease BEFREE Rap2B expression is up-regulated in glioma tissues and glioma cell lines. 30997639 2019
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 AlteredExpression disease BEFREE We investigated miR-708 function in glioma and revealed that miR-708 expression was significantly down-regulated in glioma tissues and cell lines. 31171769 2019
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 Biomarker disease BEFREE MiR-1231 has been reported to be down-regulated in glioma tissues and to act as a negative regulator in glioma progression. 30556881 2018
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 Biomarker disease BEFREE Here, we found that miRNA-320c was significantly down-regulated in glioma tissues in contrast with normal brain tissues, being tightly related to clinical stage of glioma by qRT-PCR. 29438779 2018
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 Biomarker disease BEFREE Additionally, IRG1 was markedly up-regulated in glioma and was confirmed as a direct target for miR 378 in glioma. 29949160 2018
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 AlteredExpression disease BEFREE Additionally, we reported that miR125a-5p was down-regulated in glioma as well as statistical analysis suggested that its expression level correlated with the World Health Organization grades of glioma (P < 0.05) and that patients with a low miR125a-5p level exhibited shorter survival time (P < 0.05). 25598421 2016
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 Biomarker disease BEFREE HOTTIP was aberrantly down-regulated in glioma tissues and glioma cell lines (U87-MG, U118-MG, U251 and A172), and over-expression of HOTTIP inhibited the growth of glioma cell lines in vitro and in vivo. 27733185 2016
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 AlteredExpression disease BEFREE Here, we found that RACK1 was significantly up-regulated in glioma tissues compared with normal brain tissues, being closely related to clinical stage of glioma both in mRNA and protein levels. 27763568 2016
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 Biomarker disease BEFREE Independent validation with glioma patients tissue (<i>n</i> = 70) and normal brain tissue (<i>n</i> = 19) found <i>PPIC</i>, <i>EMP3</i> and <i>CHI3L1</i> were up-regulated in glioma tissue. 27801851 2016
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 AlteredExpression disease BEFREE The levels of p-GSK-3β (Ser9), but not total GSK-3β, are significantly up-regulated in glioma tissues compared to normal tissues, and are significantly correlated with the glioma grades. 26388612 2015
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 AlteredExpression disease BEFREE Our results demonstrated that PTTG expression was significantly up-regulated in glioma, and had positive correlation with glioma grade and MVD. 25908389 2015
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 Biomarker disease BEFREE CELF1 is Up-Regulated in Glioma and Promotes Glioma Cell Proliferation by Suppression of CDKN1B. 26535026 2015
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 Biomarker disease LHGDN REIC/Dkk-3 induces cell death in human malignant glioma. 18443132 2008
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
0.100 GeneticVariation disease BEFREE Genomic alterations of RIG were present in approximately 25% of glioma cell lines examined. 9070656 1997