Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406913
Gene Symbol: MIR126
MIR126
0.090 Biomarker disease BEFREE LncRNA-XIST/microRNA-126 sponge mediates cell proliferation and glucose metabolism through the IRS1/PI3K/Akt pathway in glioma. 31680298 2020
Entrez Id: 406913
Gene Symbol: MIR126
MIR126
0.090 Biomarker disease BEFREE The miR-126 expression is abnormally low in glioma cells, and miR-126 inhibits the course of glioma through targeted regulation of PTEN/PI3K/Akt and MDM2-p53 pathways, which, therefore, can be used as a new potential biomarker for the diagnosis, treatment and prognosis of glioma. 31081101 2019
Entrez Id: 406913
Gene Symbol: MIR126
MIR126
0.090 Biomarker disease BEFREE Taken together, our study clarified that the HOTAIR/miR-126/GLS pathway is involved in glioma progression and may potentially serve as a target for glioma therapy. 29319172 2018
Entrez Id: 406913
Gene Symbol: MIR126
MIR126
0.090 Biomarker disease BEFREE Taken together, we concluded that miR-126 enhances the formation of glioma cancer stem cell probably via down regulation of IRS-1 in neurotrophin signaling pathway. 29633591 2018
Entrez Id: 406913
Gene Symbol: MIR126
MIR126
0.090 AlteredExpression disease BEFREE Many microRNAs (miRNAs) such as miR-183, miR-9, miR-137 and miR-126 expression change may be involved in the cross talk between glioma prevalence and schizophrenia. 30233327 2018
Entrez Id: 406913
Gene Symbol: MIR126
MIR126
0.090 Biomarker disease BEFREE We aimed to explore the relationship between miR-126 and glioma. miR-126 was highly expressed in low-grade clinical glioma tissue samples but lowly expressed in high-grade ones (P < .01). 27598297 2017
Entrez Id: 406913
Gene Symbol: MIR126
MIR126
0.090 Biomarker disease BEFREE Kirsten rat sarcoma viral oncogene (KRAS) which is involved in ERK pathway was directly targeted by miR-126 in glioma through binding to two sites in the 3' untranslated region (3'-UTR) of KRAS mRNA. 26732596 2017
Entrez Id: 406913
Gene Symbol: MIR126
MIR126
0.090 Biomarker disease BEFREE In the present study, we aimed to verify the miRNA-126 down-regulation which showed in the results of glioma tissue miRNAs chip and discuss the miRNA-126 methylation in patients with glioma. 26463235 2016
Entrez Id: 406913
Gene Symbol: MIR126
MIR126
0.090 Biomarker disease BEFREE Taken together, these findings showed that miR-126 functions as a tumor suppressor in glioma cells by targeting IRS-1 expression via the PI3K/AKT signaling pathways, suggesting that miR-126 might be a novel target for therapeutic strategies in glioma. 26617742 2015