Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4192
Gene Symbol: MDK
MDK
0.340 AlteredExpression disease BEFREE DNA damage repair alterations modulate M2 polarization of microglia to remodel the tumor microenvironment via the p53-mediated MDK expression in glioma. 30773478 2019
Entrez Id: 4192
Gene Symbol: MDK
MDK
0.340 AlteredExpression disease BEFREE MDK and SP1 expression in gliomas was significantly higher than in adjacent tissues and was positively correlated in glioma clinical samples and cell lines. 25428991 2015
Entrez Id: 4192
Gene Symbol: MDK
MDK
0.340 AlteredExpression disease BEFREE The expression levels of MK and PTN proteins in glioma tissue were both significantly higher (both p<0.001) than those in paratumor tissues on immunohistochemistry analysis, which was confirmed by qRT-PCR analysis. 25001988 2014
Entrez Id: 4192
Gene Symbol: MDK
MDK
0.340 Biomarker disease CTD_human Altogether, our findings identify Mdk as a pivotal factor involved in the resistance of glioma cells to THC pro-autophagic and antitumoral action, and suggest that selective targeting of the Mdk/ALK axis could help to improve the efficacy of antitumoral therapies for gliomas. 21233844 2011
Entrez Id: 4192
Gene Symbol: MDK
MDK
0.340 Biomarker disease LHGDN In an animal experiment, Ad-MK completely eradicated midkine-positive glioma xenografts. 15201962 2004