| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | AlteredExpression | disease | BEFREE | TNF-α stimulation further upregulated the expression of NF-κB1, STAT-6 in tandem with Ras-MEK signaling system in U87MG cells, which emphasized the possible involvement of these signaling hubs in the glioma microenvironment. | 30839135 | 2019 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | NFKB1 -94ins/delATTG and TLR4Asp299Gly polymorphisms are associated with increased glioma cancer risk in a Turkish population. | 30450997 | 2019 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | A del/ins polymorphism of the NF-κB1 gene (OR 4.27, 95% CI 2.43-7.50, p<0.001) was also found to be associated with glioma. | 28777431 | 2018 | ||||
|
0.090 | Biomarker | disease | BEFREE | Thus, high-grade glioma T cells play a key role in directing M2 polarization of tumor myeloid cells, and reducing NF-κB p50 in both tumor myeloid cells and T cells may contribute to glioma therapy. | 30030559 | 2018 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Results showed that the expression of NF-κB1 in human glioma tissues and glioma cell lines, SHG44 and U87, was significantly higher compared to noncancerous brain tissues and that the expression increased with increasing degrees of tumor malignancy. | 28919779 | 2017 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | p68 RNA helicase promotes glioma cell proliferation in vitro and in vivo via direct regulation of NF-κB transcription factor p50. | 22810421 | 2012 | ||||
|
0.090 | AlteredExpression | disease | LHGDN | Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1. | 18316612 | 2008 | ||||
|
0.090 | Biomarker | disease | LHGDN | Pregabalin and gabapentin inhibit substance P-induced NF-kappaB activation in neuroblastoma and glioma cells. | 18615578 | 2008 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Aneuploid nuclei of glial tumors showed enhanced expression of p105 relative to diploid cells of the same specimen. | 2377285 | 1990 |